| Description |
1 online resource (1 PDF file (xii, 107 pages)) : illustrations |
| Physical Medium |
polychrome |
| Description |
text file |
| Bibliography |
Includes bibliographical references. |
| Summary |
The marmoset, a type of small monkey native to South America, is a research model of increasing importance for biomedical research in the United States and globally. Marmosets offer a range of advantages as animal models in neuroscience, aging, infectious diseases, and other fields of study. They may be particularly useful for the development of new disease models using genetic engineering and assisted reproductive technologies. However, concerns have been voiced with respect to the development of new marmoset-based models of disease, ethical considerations for their use, the supply of marmosets available for research, and gaps in guidance for their care and management. To explore and address these concerns, the Roundtable on Science and Welfare in Laboratory Animal Use hosted a public workshop on October 22-23, 2018, in Washington, DC. The workshop focused on the availability of marmosets in the United States and abroad; animal welfare and ethical considerations stemming from the use of wildtype and genetically modified marmosets; and standards of housing and care, dietary needs, and feeding requirements for marmosets in captivity. This publication summarizes the presentations and discussions from the workshop. |
| Funding |
This project was supported by the American Veterinary Medical Association; Association of Primate Veterinarians; Baylor College of Medicine; Broad Institute; Charles River Laboratories; Emory University; Genentech; GlaxoSmithKline; Indiana University; Janssen Research & Development, LLC; Japan Agency for Medical Research and Development; Johns Hopkins University; Johnson & Johnson/Janssen Pharmaceuticals; Massachusetts General Hospital; Massachusetts Institute of Technology (MIT); McGovern Institute for Brain Research at MIT; Medical College of Wisconsin; MedImmune; Merck and Co., Inc.; National Institutes of Health (Contract No. HHSN263201800029I; Task Order HHSN26300016); National Primate Research Centers; Novartis; Pfizer Inc.; University of Miami; University of Michigan; University of Pittsburgh; Wisconsin National Primate Research Center; and Yale University. Funding for this workshop was made possible, in part, by the U.S. Department of Agriculture through grant AP17AC000000G004 and the U.S. Food and Drug Administration through grant 5 R13 FD 005298-05. Views expressed in written workshop materials or publications and by speakers or moderators do not necessarily reflect the official policies of the U.S. Department of Health and Human Services; nor does any mention of trade names, commercial practices, or organizations imply endorsement by the U.S. government. This material is based on work supported by the National Science Foundation under Grant No. IOS-1639899. Any opinions, findings, and conclusions or recommendations expressed in this material are those of the authors and do not necessarily reflect the views of the National Science Foundation. Any opinions, findings, conclusions, or recommendations expressed in this publication do not necessarily reflect the views of any organization or agency that provided support for the project. |
| Contents |
Introduction -- Context for the use of marmosets as animal models -- Ethical considerations -- Current research applications -- Marmoset genomics and genetic diversity -- Marmoset care and management -- Final remarks -- Appendixes |
| Local Note |
eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America |
| Subject |
Marmosets as laboratory animals -- Moral and ethical aspects -- United States -- Congresses.
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Marmosets as laboratory animals. |
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United States. |
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Laboratory animals -- Moral and ethical aspects -- United States -- Congresses.
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Laboratory animals -- Moral and ethical aspects. |
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Laboratory animals. |
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Gene editing -- Moral and ethical aspects -- United States -- Congresses.
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Gene editing. |
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Laboratory animals.
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Callithrix.
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Callithrix. |
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Diseases -- Animal models.
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Diseases -- Animal models. |
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United States. |
| Genre/Form |
Congress.
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Conference papers and proceedings.
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Conference papers and proceedings.
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Technical reports.
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Technical reports.
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| Added Author |
Anestidou, Lida, 1965- rapporteur.
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Institute for Laboratory Animal Research (U.S.). Roundtable on Science and Welfare in Laboratory Animal Use, issuing body.
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Care, Use, and Welfare of Marmosets as Animal Models for Gene Editing-Based Biomedical Research (Workshop) (2018 : Washington, D.C.)
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| Other Form: |
Print version:National Academies of Sciences, Engineering, and Medicine. Care, use, and welfare of marmosets as animal models for gene editing-based biomedical research. Washington, DC: National Academies Press, 2019 0309488516 (OCoLC)1105705799 |
| ISBN |
9780309488518 |
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0309488516 |
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9780309488525 (electronic book) |
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0309488524 (electronic book) |
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9780309488549 (electronic book) |
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0309488540 (electronic book) |
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