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Bestseller
BestsellerE-book
Author Ehlert, Frederick J., author.

Title Affinity and efficacy : the components of drug-receptor interactions / Frederick J. Ehlert.

Publication Info. New Jersey : World Scientific, [2014]

Item Status

Description 1 online resource
Physical Medium polychrome
Description text file
Bibliography Includes bibliographical references.
Contents Ligand-gated ion channels -- Affinity and efficacy of orthosteric ligands at ligand-gated ion channels -- Competitive interactions between orthostheric ligands at ligand-gated ion channels -- Analysis of allosteric interactions at ligand-gated ion channels -- G protein-coupled receptors and G protein signaling -- Affinity and efficacy of the agonist-receptor-G-protein interaction -- Estimating affinity and efficacy by reverse-engineering and response-clamp analysis -- Analysis of agonism and inverse agonism in signaling pathways that exhibit constitutive activity -- Analysis of ligand bias in receptor signaling through different G protein pathways -- Competitive interactions between orthosteric ligands in functional assays on G protein-coupled receptors -- Analysis of allosterism in functional assays on G protein-coupled receptors -- Analysis of drug-receptor interactions using radioligand binding assays on G protein-coupled receptors.
Local Note eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America
Subject Drug receptors.
Drug receptors.
Drugs -- Effectiveness.
Drugs -- Effectiveness.
Drug-nutrient interactions.
Drug-nutrient interactions.
Pharmaceutical chemistry.
Pharmaceutical chemistry.
Receptors, Drug.
Ligand-Gated Ion Channels.
Protein Binding.
Radioligand Assay.
Receptors, G-Protein-Coupled.
Genre/Form Electronic books.
Subject Medication.
Added Title Components of drug-receptor interactions
Other Form: Print version: Ehlert, Frederick J. Affinity and efficacy 9789814322560 (DLC) 2014024093 (OCoLC)639162607
ISBN 9789814324229 (electronic book)
9814324221 (electronic book)
9789814322560
9814322563