| Description |
1 online resource. |
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data file |
| Series |
Nanotechnology science and technology
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Nanotechnology science and technology series.
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| Bibliography |
Includes bibliographical references and index. |
| Contents |
Intro -- SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES: SYNTHESIS, SURFACE ENGINEERING, CYTOTOXICITY AND BIOMEDICAL APPLICATIONS -- SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES: SYNTHESIS, SURFACE ENGINEERING, CYTOTOXICITY AND BIOMEDICAL APPLICATIONS -- LIBRARY OF CONGRESS CATALOGING-IN-PUBLICATION DATA -- DEDICATION -- ABOUT THE AUTHORS -- CONTENTS -- PREFACE -- Chapter 1 INTRODUCTORY TO THE BOOK -- 1.1. SEMICONDUCTING NANOPARTICLES -- 1.2. IRON OXIDE NANOPARTICLES -- 1.3. BIOMINERALIZATION -- 1.4. TYPES OF MAGNETIC IRON OXIDES -- 1.5. SYNTHESIS OF SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES (SPIONS): CHEMICAL COPRECIPITATION -- 1.6. DESIGN OF EXPERIMENTS (DOE) FOR SYNTHESIS OF SPIONS -- REFERENCES -- Chapter 2 SYNTHESIS OF SPIONS -- 2.1. NUCLEATION OF NANOPARTICLES -- 2.2. SYNTHESIS METHODS -- 2.2.1. Chemical Methods -- 2.2.1.1. Co-precipitation -- 2.2.1.2. Microemulsions -- 2.2.1.3. Hydrothermal -- 2.2.1.4. Thermal Decomposition -- 2.2.1.5. Sol-gel -- 2.2.1.6. Polyol -- 2.2.1.7. Sonochemical -- 2.2.1.8. Electrochemical Deposition -- 2.2.2. Physical Methods -- 2.2.2.1. Flow Injection -- 2.2.2.2. Aerosol/Vapor -- 2.2.2.3. Pulsed Laser Ablation -- 2.2.2.4. Laser Induced Pyrolysis -- 2.2.2.5. Powder Ball Milling -- 2.2.3. Biological/ Bio-mineralization -- REFERENCES -- Chapter 3 APPLICATION OF STATISTICAL TECHNIQUES -- 3.1. THE TWO SAMPLE T-TEST -- 3.2. HYPOTHESIS TESTING FOR OUTLIER DETECTION -- GRUBBS' TEST -- 3.3. DESIGN OF EXPERIMENTS -- Remark: How to Perform the Analysis with More than Two Factors, Two Levels? -- 3.3.1. Checking Model Assumptions: Effect of Potentially Outlying Observations -- REFERENCES -- Chapter 4 COATINGS OF SPIONS -- 4.1. COLLOIDAL STABILITY OF SPIONS -- 4.2. POLYMERIC COATING -- 4.2.1. Polyethylene Glycol -- 4.2.2. Polyethylene Glycol Fumarate -- 4.2.3. Polyvinyl Alcohol -- 4.2.4. Polyacrylic Acid. |
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4.2.5. Poly(N-isopropylacrylamide) -- 4.2.6. Dextran -- 4.2.7. Poly(D, L-lactide) -- 4.2.8. Poly(D, L-lactide-co-glycolide) -- 4.2.9. Alginate -- 4.2.10. Chitosan and Polyethylenimine -- 4.3. NON-POLYMERIC COATING -- 4.3.1. Gold -- 4.3.2. Silica -- 4.4. FUNCTIONALIZATION OF SPIONS -- REFERENCES -- Chapter 5 CYTOTOXICITY OF SPIONS -- 5.1. BIOCOMPATIBILITY VERSUS TOXICITY -- 5.1.1. Biocompatibility -- 5.1.2. Cytotoxicity -- 5.2. IN VITRO TOXICITY ASSAYS -- 5.2.1. Metabolic Activity -- 5.2.1.1. MTT Assay -- 5.2.1.1.1. Modification of MTT Method -- 5.2.1.2. MTS and XTT Assays -- 5.2.1.2.1. MTS Assay -- 5.2.1.2.2. XTT Assay -- 5.2.1.3. Redox Assay -- 5.2.1.4. Adenosine Triphosphate Assay -- 5.12.1.5. Cytochrome C Assay -- 5.2.1.6. Nitroblue Tetrazolium (NBT) Assay -- 5.2.1.7. WST Assay -- 5.2.2. Membrane Integrity -- 5.2.2.1. LDH Assay -- 5.2.2.2. The Calcein AM, Live/Dead and Ethidium Homodimer Assay -- 5.2.2.3. Dye Assays -- 5.2.2.3.1. Erythrosine B (EB) Assay -- 5.2.2.3.2. Propidium Iodide (PI) Assay -- 5.2.2.3.3. Neutral Red (NR) Assay -- 5.2.2.3.4. Bromodeoxyuridine (BrdU) Assay -- 5.2.2.3.5. Trypan Blue (TB) Assay -- 5.2.2.3.6. DNA Hoechst Assay -- 5.2.2.3.7. Other Dye Assays -- 5.2.3. Cell Proliferation Assay -- 5.2.3.1. Cell Cycle Assay -- 5.2.3.2. [3H] Thymidine Incorporation Assay -- 5.2.4. Apoptosis Detection -- 5.2.4.1. Flow Cytometry -- 5.2.4.2. Comet Assay -- 5.3. IN VIVO TOXICITY -- 5.4. PHARMACOKINETICS AND BIODISTRIBUTION -- REFERENCES -- Chapter 6 APPLICATION OF SPIONS* -- 6.1. SPIONS AS MAGNETIC RESONANCE IMAGING CONTRAST AGENT -- Introduction -- Paramagnetic Agents -- Superparamagnetic Agents -- Current Clinical Use of (U)SPIONs as Contrast Agents -- Oral Contrast Agents -- Injectable Contrast Agents -- Ferumoxides (Feridex I.V./Endorem) -- Ferucarbotran/SHU555A (Resovist/Cliavist) -- Ferumoxtran-10 (USPIO) (Combidex/Senerem). |
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PEG-feron (Feruglose/Clariscan) -- Ferucarbotran (USPIO)/SHU555C (Supravist) -- Ferumoxytol (USPIO) (Feraheme) -- 6.2. SPIONS FOR MAGNETIC LABELING OF CELLS -- Introduction -- SPIONs and its Modification for Labeling -- Transfection Agents Mediated Modification of SPIONs for Cell Labeling -- Optimization of Cell Labeling with Simple Incubation -- Assay to Determine the Toxicity of Labeling -- 6.3. SPIONS AND MAGNETICALLY LABELED CELLS FOR MULTIMODAL REGIMENS -- SPIONs for Multimodal Imaging -- Cells for Multimodal Imaging -- 6.4. SPIONS AS DRUG DELIVERY VEHICLES -- Introduction -- Active Targeting Using Ligand Substrate Mechanisms, Antigen-Antibody or Receptors -- Enhanced Permeability Retention (EPR) Effect -- Convection-Enhanced Delivery -- Magnet Activated Delivery -- Drug Delivery by Direct Injection -- 6.5. SPIONS FOR HYPERTHERMIA TREATMENT -- 6.6. SPIONS FOR ENHANCED TRANSFECTION OF DNA (MAGNETOFECTION) -- 6.7. SPIONS FOR CELL/PROTEIN SEPARATION -- 6.8. SPIONS AS CATALYST -- 6.9. SPIONS FOR TISSUE REPAIR -- REFERENCES -- INDEX. |
| Local Note |
eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America |
| Language |
English. |
| Subject |
Nanomedicine.
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Nanomedicine. |
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Ferric oxide -- Magnetic properties.
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Ferric oxide. |
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Nanoparticles.
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Nanoparticles. |
| Genre/Form |
Electronic books.
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| Added Author |
Mahmoudi, Morteza, 1979-
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| Other Form: |
Print version: Superparamagnetic iron oxide nanoparticles New York : Nova Science Publishers, c2011. 9781616689643 (hardcover) (DLC) 2010036438 |
| ISBN |
9781617286315 ebook |
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1617286311 |
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1616689641 hardcover |
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9781616689643 hardcover |
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