LEADER 00000cam a2200673 a 4500 001 ocn801916879 003 OCoLC 005 20190712071343.4 006 m o d 007 cr cn||||||||| 008 120614s2012 cau ob 000 0 eng 016 7 101586328|2DNLM 019 847890378|a867483850|a903552990 020 9780833079848 020 0833079840 027 RAND/TR-1247-AMGEN 035 (OCoLC)801916879|z(OCoLC)847890378|z(OCoLC)867483850 |z(OCoLC)903552990 037 22573/ctt36svrk|bJSTOR 040 NLM|beng|epn|cNLM|dKLG|dOCLCF|dRSM|dJSTOR|dYDXCP|dTEF |dOCLCQ|dOCLCO|dCUS|dOCLCQ|dLND|dLOA|dNLM|dOCLCO|dICG|dU3W |dERL|dOCLCA 042 pcc 043 e------ 049 RIDW 050 4 RC931.O73|b.P68 2012 082 04 616.7/16|223 090 RC931.O73|b.P68 2012 245 00 Postmanopausal osteoporosis management :|ba review of the evidence to inform the development of quality indicators / |cAnnalijn Conklin [and others] ; prepared for Amgen. 264 1 Santa Monica, CA :|bRAND Europe,|c2012. 300 1 online resource (xv, 110 pages). 336 text|btxt|2rdacontent 337 computer|bc|2rdamedia 338 online resource|bcr|2rdacarrier 340 |gpolychrome|2rdacc 347 text file|2rdaft 490 1 Technical report ;|vTR-1247-AMGEN 504 Includes bibliographical references. 505 0 Introduction -- The diagnosis, prevention and treatment of postmenopausal osteoporosis -- Managing postmenopausal osteoporosis in Europe -- Informing the development of quality indicators for the management of postmenopausal osteoporosis -- Appendix A: Overview of guidelines in place in four countries -- Appendix B: Interview topic guide. 520 3 This report aims to inform the development of quality indicators for postmenopausal osteoporosis management through: (a) assessing the evidence for screening and diagnosis of osteoporosis and related risk factors, and for prevention and treatment of osteoporosis and osteoporosis-related fractures; (b) describing current practice for managing postmenopausal osteoporosis in Europe; and (c) highlighting existing gaps in the evidence base and management practices in Europe. Analyses involved a comprehensive review of reviews regarding the screening and diagnosis of osteoporosis and related risk factors and the prevention and treatment of osteoporosis and osteoporosis-related fractures. While this identified a well developed evidence base on the effects of selected treatments on clinical outcomes of postmenopausal osteoporosis and associated fractures, and on the usefulness of selected simple risk factor assessment tools to identify postmenopausal women who would benefit from further diagnostic assessment, uncertainties remain regarding for example the optimal use of pharmacological interventions for preventive purposes and the effectiveness of population-based screening. We also carried out case study reviews of current practices for managing postmenopausal osteoporosis in England, France, Germany and Spain. We identify a need for the establishment of routine monitoring systems to enable better understanding of contemporary patterns and trends and identify care gaps in the management of postmenopausal osteoporosis and associated fractures. Such analyses are crucial to inform targeted strategies and policies to effectively address the burden of osteoporosis and associated fractures, which is sizable and set to increase across Europe. We set out considerations as a starting point for the further development of quality measures for postmenopausal osteoporosis in Europe. 588 0 Online resource; title from PDF title page (viewed on July 9, 2012). 590 JSTOR|bBooks at JSTOR Open Access 650 0 Osteoporosis in women|0https://id.loc.gov/authorities/ subjects/sh97008285|zEurope.|0https://id.loc.gov/ authorities/subjects/sh85045631-781 650 0 Evidence-based medicine|0https://id.loc.gov/authorities/ subjects/sh97007984|zEurope.|0https://id.loc.gov/ authorities/subjects/sh85045631-781 650 7 Osteoporosis in women.|2fast|0https://id.worldcat.org/fast /1048832 650 7 Evidence-based medicine.|2fast|0https://id.worldcat.org/ fast/917247 651 2 Europe.|0https://id.nlm.nih.gov/mesh/D005060 651 7 Europe.|2fast|0https://id.worldcat.org/fast/1245064 655 2 Review.|0https://id.nlm.nih.gov/mesh/D016454 655 4 Electronic books. 700 1 Conklin, Annalijn.|0https://id.loc.gov/authorities/names/ n2010184853 710 2 RAND Europe.|0https://id.loc.gov/authorities/names/ n97080747 710 2 Amgen Inc.|0https://id.loc.gov/authorities/names/ nr94015151 830 0 Technical report (Rand Corporation) ;|0https://id.loc.gov/ authorities/names/n2005069635|vTR-1247-AMGEN. 856 40 |uhttps://www.jstor.org/stable/10.7249/j.ctt3fh1vm|zOnline eBook. Open Access via JSTOR. 901 MARCIVE 20231220 948 |d20190820|cJSTOR EBSCO|tJSTOROpenAccess EBSCOebooksacademic UPDATES 5472J 1248 BOTH 7-12-19|lridw 948 |d20180926|clti|tlti-aex 948 |d20171005|cJSTOR|tJSTOROpenAccess new|lridw 994 92|bRID