| Description |
1 online resource (xii, 303 pages) : illustrations (some color). |
|
text file |
| Series |
RSC biomolecular sciences,
1757-7152 ;
no. 26
|
|
RSC biomolecular sciences ; 26.
|
| Bibliography |
Includes bibliographical references and index. |
| Summary |
"Applications of nucleic acids have developed recently to provide solutions for biosensors, diagnostic tools and as platforms for the assembly of complex structures. These developments have been possible as their base sequence can be used to assemble precise structures following simple and predictable rules. Self-assembled DNA can then be amplified using polymerase chain reaction (PCR) and this ultimately enables the preparation of synthetic nucleic acids. Their use as molecular tools or DNA-conjugates has recently been enhanced by the addition of other groups including enzymes, fluorophores and small molecules. Written by leaders in the field, this volume describes the preparation and application of these DNA-conjugates. Several have been used as sensors (aptamers, riboswitches and nanostructures) based on the ability of nucleic acids to adopt specific structures in the presence of ligands, whilst others link reporter groups such as proteins or fluorophores to RNA or DNA for detection, single molecule studies, and increasing the sensitivity of PCR. The book will interest researchers in areas related to analytical chemistry, chemical biology, medicinal chemistry, molecular pharmacology, and structural and molecular biology."-- Provided by publisher. |
| Local Note |
eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America |
| Subject |
DNA -- Synthesis.
|
|
DNA -- Synthesis. |
|
DNA -- biosynthesis. |
|
Aptamers, Nucleotide -- biosynthesis. |
|
Biosensing Techniques. |
| Genre/Form |
Electronic books.
|
| Added Author |
Fox, Keith R.
|
|
Brown, Tom (Biochemist)
|
| Other Form: |
Print version: DNA conjugates and sensors. Cambridge : RSC Publishing, ©2012 9781849734271 (OCoLC)821679580 |
| ISBN |
1849734933 (electronic book) |
|
9781849734936 (electronic book) |
|
9781849734271 (hardback) |
|
1849734275 (hardback) |
| Standard No. |
10.1039/9781849734936 |
|
