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001 ocn989063219
003 OCoLC
005 20200717185938.7
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008 170606s2017 mau ob 001 0 eng d
019 1004875510
020 9780674978638|q(electronic book)
020 0674978633|q(electronic book)
020 |z9780674972087
020 |z0674972082
024 7 10.4159/9780674978638|2doi
035 (OCoLC)989063219|z(OCoLC)1004875510
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050 4 QR370|b.C67 2017eb
072 7 SCI|x008000|2bisacsh
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072 7 SCI099000|2bisacsh
072 7 SCI027000|2bisacsh
072 7 MED022090|2bisacsh
082 04 579.2|223
090 QR370|b.C67 2017eb
100 1 Cordingley, Michael G.,|d1958-|0https://id.loc.gov/
authorities/names/no2017004364|eauthor.
245 10 Viruses :|bagents of evolutionary invention /|cMichael G.
Cordingley.
264 1 Cambridge, Massachusetts :|bHarvard University Press,
|c2017.
264 4 |c©2017
300 1 online resource (vii, 373 pages)
336 text|btxt|2rdacontent
337 computer|bc|2rdamedia
338 online resource|bcr|2rdacarrier
340 |gpolychrome|2rdacc
347 text file|bPDF|2rda
504 Includes bibliographical references and index.
505 0 1. Obligate parasites of cells: Discovery -- The
virosphere and its metagenome -- Complexity and "dark
matter" -- Selfish information and the essence of being
viral -- The emergence of egotistical replicators -- The
viral empire -- 2. Viruses, genes, and ecosystems:
Lifestyles and life cycles -- Lysogeny: exercising
temperance -- Kill the winner -- Gene brokers --
Selfishness driving adaptive evolution -- Phages and the
microbiome -- Unfriendly competition -- Chemical warfare -
- 3. Potentiation of bacterial diseases by phages: For a
charm of powerful trouble -- Toxic enablers -- Choose your
poison -- Treasure islands -- Prophage induction and
antibiotic drug resistance -- 4. Viruses and higher
organisms: Viruses, cells, organisms, and populations --
"Just a virus" -- Human rhinoviruses -- Uncommon diversity
-- Accidents of pathogenesis -- Mutation, diversity, and
quasipecies -- 5. The flu: no common cold: Antigenic
escape artists -- Human influenza a virus -- Epidemic
influenza: dress for the season -- Quasispecies, sequence
clusters, and codon bias -- Correlating genetic and
antigenic evolution -- Seeding of seasonal epidemics --
Pandemic influenza: the emperor with no clothes -- 6.
Alternative virus lifestyles: Latency: 'til death do us
part -- All in the family Herpesviridae -- 7. Evolutionary
mechanisms of DNA viruses: Gene duplication and gene
capture -- Poxvirus evolution -- Poxvirus party tricks --
Small DNA virus evolution -- 8. Viroids and megaviruses:
extremes: Viroids: the smallest -- Evolutionary reliquary
-- Megaviruses: the biggest -- Big and bigger --
Virophages: fleas upon fleas -- Chimerism -- Megavirus
origins: mavericks at heart -- 10. HIV-1: a very modern
pandemic: A new disease and a new virus -- Anatomy of HIV-
1 -- HIV in the making -- Socioepidemiology of AIDS: a man
-made epidemic -- Within-host evolution: a very personal
arms race -- Short-sighted evolution -- Adaptive evolution
: an evolving relationship -- Outrunning the red queen --
Medicine at the virus-host interface -- Resistance is
futile -- 10. Cross-species infections: means and
opportunity: A rogue's gallery of emerging viruses --
Adaptive evolution in zoonosis -- Fitness landscape -- A
shifting fitness landscape -- The paradox in RNA virus
evolution -- RNA viruses and molecular clocks --
Arboviruses: vector-borne viruses -- Evolutionary
compromise -- Host restriction -- 11. Future pandemic
influenza: enemy at the gates: Real and present danger --
Pandemic threat level -- The pandemic phenotype --
Outbreak -- 12. Ebolavirus: EBOV Makona -- What we were
afraid to say about Ebola -- Evolution or adaptive change
-- EBOV persistence -- 13. Viral zoonoses and animal
reservoirs: The usual suspects -- Filovirus origins --
Bats and viral zoonoses -- A special relationship --
Tolerance and resistance -- 14. Endogenous retroviruses:
our viral heritage: Genome invasion by retroviruses --
Endogenization in progress -- Change agents --
Domestication of ERV genes -- Endogenous viral elements --
15. Viruses as human tools: Myxoma virus: biological
control -- Genomics of an attenuated poxvirus --
Orthopoxviruses: past solutions and future problems --
Live-attenuated viruses -- Attenuation by design -- Virus
therapeutics -- Doctor's little helpers -- Oncolytic
viruses -- 16. Humanity and viruses: The human future and
viruses -- Beauty in design.
520 Viruses are the most abundant biological entities on Earth,
and arguably the most successful. They are not technically
alive, but--as infectious vehicles of genetic information-
-they have a remarkable capacity to invade, replicate, and
evolve within living cells. Synthesizing a large body of
recent research, Michael Cordingley goes beyond our
familiarity with viral infections to show how viruses spur
evolutionary change in their hosts, shape global
ecosystems, and influence every domain of life. In the
past few decades, research has revealed that viruses are
fundamental to the photosynthetic capacity of the world's
oceans and the composition of the human microbiome.
Perhaps most fascinating, viruses are now recognized as
remarkable engines of the genetic innovation that fuels
natural selection and catalyzes evolution in all domains
of life. Viruses have coevolved with their hosts since the
beginning of life on our planet and are part of the
evolutionary legacy of every species that has ever lived.
Cordingley explains how viruses are responsible for the
creation of many feared bacterial diseases and the
emergence of newly pathogenic and drug-resistant strains.
And as more and more viruses jump to humans from other
animals, new epidemics of viral disease will threaten
global society. But Cordingley shows that we can adapt,
relying on our evolved cognitive and cultural capacities
to limit the consequences of viral infections.--|cProvided
by publisher.
546 In English.
588 0 Online resource; title from PDF title page (EBSCO, viewed
June 6, 2017).
590 eBooks on EBSCOhost|bEBSCO eBook Subscription Academic
Collection - North America
650 0 Viruses.|0https://id.loc.gov/authorities/subjects/
sh85143833
650 0 Evolution (Biology)|0https://id.loc.gov/authorities/
subjects/sh90004042
650 7 Viruses.|2fast|0https://id.worldcat.org/fast/1167771
650 7 Evolution (Biology)|2fast|0https://id.worldcat.org/fast/
917302
655 4 Electronic books.
856 40 |uhttps://rider.idm.oclc.org/login?url=http://
search.ebscohost.com/login.aspx?direct=true&scope=site&
db=nlebk&AN=1527408|zOnline ebook via EBSCO. Access
restricted to current Rider University students, faculty,
and staff.
856 42 |3Instructions for reading/downloading the EBSCO version
of this ebook|uhttp://guides.rider.edu/ebooks/ebsco
901 MARCIVE 20231220
948 00 |d20200727|cEBSCO|tEBSCOebooksacademic NEW June-July 17
7032|lridw
994 92|bRID
