| Description |
1 online resource (x, 192 pages) : illustrations. |
| Physical Medium |
polychrome |
| Description |
text file |
| Series |
Special publication ; no. 279
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Special publication (Royal Society of Chemistry (Great Britain)) ; no. 279.
|
| Note |
"The proceedings of the meeting on Cutting Edge Approaches to Drug Design held on 13 March 2001 at the Scientific Societies Lecture Theatre, London, UK"--Title page verso. |
| Bibliography |
Includes bibliographical references and index. |
| Contents |
Molecular informatics : sharpening drug design's cutting edge -- High-throughput X-ray crystallography for drug discovery -- Trawling the genome for G protein-coupled receptors : the importance of integrating bioinformatic approaches -- Virtual screening of virtual libraries : an efficient startegy for lead generation -- Virtual techniques for lead optimisation -- The impact of physical organic chemistry on the control of drug-like properties -- Mutagenesis and modelling highlight the critical nature of the TM2-loop-TM3 region of biogenic amine GPCRs -- Computational vaccine design. |
| Summary |
Pharmaceutical research draws on increasingly complex techniques to solve the challenges of drug design. Bringing together a number of the latest informatics techniques, this book looks at modelling and bioinformatic strategies; structural genomics and X-ray crystallography; virtual screening; lead optimisation; ADME profiling and vaccine design. A number of relevant case studies, focussing on techniques that have demonstrated their use, will concentrate on G-protein coupled receptors as potential disease targets. Providing details of state-of-the-art research, Drug Design: Cutting Edge Approaches will be invaluable to all drug discovery scientists, including medicinal and combinatorial chemists, molecular modellers, bio- and chemoinformaticians, and pharmacologists, amongst others. |
| Access |
Use copy Restrictions unspecified MiAaHDL |
| Reproduction |
Electronic reproduction. [S.l.] : HathiTrust Digital Library, 2010. MiAaHDL |
| System Details |
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. http://purl.oclc.org/DLF/benchrepro0212 MiAaHDL |
| Processing Action |
digitized 2010 HathiTrust Digital Library committed to preserve MiAaHDL |
| Local Note |
eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America |
| Subject |
Drugs -- Design -- Congresses.
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Drugs -- Design. |
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Drugs -- Design -- Mathematical models -- Congresses.
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Mathematical models. |
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Artificial intelligence -- Medical applications -- Congresses.
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Artificial intelligence -- Medical applications. |
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Drugs -- Research -- Methodology -- Congresses.
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Drugs -- Research -- Methodology. |
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Drugs -- Research. |
| Genre/Form |
Electronic books.
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Congress.
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| Subject |
Medication. |
| Genre/Form |
Conference papers and proceedings.
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Conference papers and proceedings.
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| Added Author |
Flower, Darren R.
|
| Other Form: |
Print version: Drug design. Cambridge, UK : Royal Society of Chemistry, ©2002 0854048162 (DLC) 2006270060 (OCoLC)48979833 |
| ISBN |
0854048162 (electronic book) |
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9780854048168 (electronic book) |
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9781847550705 (electronic book) |
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1847550703 (electronic book) |
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