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Author Garenne, Michel, author.

Title The Niakhar high-titer measles vaccine trial, 1987-1990 / by Michel Garenne, in collaboration with Odile Leroy, Jean-Pierre Beau, Ibra Séne, Hilton Whittle, Abdourahmane Sow.

Publication Info. Newcastle upon Tyne, UK : Cambridge Scholars Publishing, 2020.
©2020

Item Status

Description 1 online resource (xix, 305 pages): illustrations, map
text file
Bibliography Includes bibliographical references and indexes.
Summary This study reports the methodology and findings of a randomized controlled vaccine trial conducted in Senegal in 1987-1990. Two high-titer measles vaccines of different strains (Edmonston-Zagreb and Schwarz) were compared with a standard vaccine (the Schwarz strain) among infants aged 5 to 10 months. Comparison focused on clinical efficacy, immunogenicity and safety. Although both high-titer vaccines induced an immunogenic response even when given at the age of 5 months, they induced a lower level of antibodies, had more vaccine failures, and were not safe, inducing an excess mortality within.
Local Note eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America
Subject Measles vaccine -- History.
Measles vaccine.
History.
Vaccination -- Senegal -- History -- 20th century.
Vaccination.
Senegal.
Chronological Term 20th century
Subject Vaccination -- Complications -- Senegal -- History -- 20th century.
Vaccination -- Complications.
Clinical trials -- Senegal -- History -- 20th century.
Clinical trials.
Senegal.
Chronological Term 1900-1999
Genre/Form History.
Added Author Leroy, Odile, contributor.
Beau, Jean--Pierre, contributor.
Séne, Ibra, contributor.
Other Form: Print version: 9781527548695 1527548694 (OCoLC)1180219619
ISBN 9781527549944 (electronic book)
1527549941 (electronic book)
9781527548695
1527548694