LEADER 00000cam a2200793Mi 4500
001 ocn872701330
003 OCoLC
005 20160527040703.8
006 m o d
007 cr |n|||||||||
008 140204s2013 gw ob 001 0 eng d
019 862939080
020 3110298309|q(electronic book)
020 9783110298307|q(electronic book)
020 |z9783110298260
020 |z3110298260
035 (OCoLC)872701330|z(OCoLC)862939080
040 CNSPO|beng|epn|cCNSPO|dOCLCO|dYDXCP|dN$T|dDEBSZ|dEBLCP
|dE7B|dIDEBK|dOCLCQ|dOCLCO
049 RIDW
050 4 RB131|b.S73 2013
072 7 QR|2lcco
072 7 HEA|x039000|2bisacsh
072 7 MED|x014000|2bisacsh
072 7 MED|x022000|2bisacsh
072 7 MED|x112000|2bisacsh
072 7 MED|x045000|2bisacsh
082 04 616/.0473|223
090 RB131|b.S73 2013
245 00 Stem cell-dependent therapies :|bmesenchymal stem cells in
chronic inflammatory disorders /|cedited by Gerhard Gross
and Thomas Häupl.
264 1 Berlin :|bDe Gruyter,|c[2013]
300 1 online resource (xviii, 408 pages .)
336 text|btxt|2rdacontent
337 computer|bc|2rdamedia
338 online resource|bcr|2rdacarrier
347 text file|2rdaft
504 Includes bibliographical references and index.
505 0 Preface; Contributing authors; 1 Mesenchymal stem cells in
the context of stem cell biology; 1.1 Introduction --
Definitions; 1.2 Embryonic and adult tissue stem cells;
1.3 Adult tissue stem cells and progenitors; 1.4 Adult
stem cells and tissue homeostasis; 1.5 Adult stem cell
niches; 1.6 Commitment and differentiation; 1.7 The case
for bone marrow MSCs; 1.8 Clinical prospects; 1.9
Concluding remark; References; 2 Are mesenchymal stem
cells immune privileged?; 2.1 Introduction -- Definition
of mesenchymal stem cells (MSCs); 2.2 The
immunosuppressive effect of MSCs on immune cells.
505 8 2.3 The potential clinical benefits of MSCs as
immunosuppressants2.4 The mechanisms of immunosuppression
by MSCs; 2.5 The mechanisms of immunosuppression by human
MSCs; 2.6 Immunosuppression by murine MSCs and the species
difference underlying the mechanisms of immunosuppression
by MSCs; 2.7 Immunosuppression mediated by fibroblasts;
2.8 The mechanisms of the immunosuppressive effect of MSCs
are shared with other nonstromal cells; 2.9 How long can
MSCs survive in vivo?; 2.10 Conclusion and discussion;
References; 3 Mesenchymal stem cell therapies for
autoimmune diseases; 3.1 Introduction.
505 8 3.2 Autoimmune disease3.3 Mesenchymal stem cells (MSCs);
3.3.1 Animal models; 3.4 Results of MSCs clinical trials;
3.5 Safety of MSCs; 3.6 Conclusion; References; 4
Mesenchymal stem cells in osteoarthritis and rheumatic
disease; 4.1 Introduction -- Rheumatic diseases; 4.2
Rheumatoid arthritis (RA); 4.3 Osteoarthritis (OA); 4.4
MSCs in healthy and rheumatic joint tissues; 4.5
Application of MSCs in rheumatic diseases; 4.6 MSCs
application in animals; 4.7 Clinical studies in humans;
4.8 Risks and benefits of MSCs treatments in rheumatic
diseases; References.
505 8 5 Mesenchymal stem cells in enthesis formation and
repair5.1 Introduction; 5.2 Structure of the tendon-to-
bone junction; 5.3 Enthesis resident T cells are involved
in enthesopathies provoking inflammation and bone
remodeling; 5.4 Biomaterials and growth factor-dependent
regeneration of tendon-to-bone junctions; 5.5
Biomechanical stimulation for enthesis repair; 5.6
Mesenchymal stem cells (MSCs); 5.7 Stem cell-dependent
approaches for repair of osteotendinous junctions; 5.8
Stem cell-dependent delivery of growth factors; 5.9 Stem
cell-dependent delivery of tenogenic transcription
factors.
505 8 5.10 Stem cell-dependent delivery of matrix
metalloproteinases5.11 Trophic activities of MSCs in
enthesis repair; 5.12 Outlook; Acknowledgment; References;
6 Mesenchymal stem cells for clinical/therapeutic
interventions of graft-versus-host disease; 6.1 Clinical
graft-versus-host disease; 6.2 Chronic graft-versus-host
disease; 6.3 Rationale to use mesenchymal stromal cells
for treatment of GvHD; 6.4 Experience of MSCs in clinical
acute graft-versus-host disease.
520 This book investigates the current state of the MSC-
dependent therapy of chronic inflammatory disorders and
autoimmune diseases. Among the covered topics are GvHD,
chronic kidney, liver and lung disease, ischemic heart and
inflammatory bowel disease, diabetes, osteoarthritis,
various rheumatic and neurological disorders, tumors and
solid organ transplantations.
588 0 Print version record.
590 eBooks on EBSCOhost|bEBSCO eBook Subscription Academic
Collection - North America
650 0 Mesenchymal Stem Cell Transplantation.
650 0 Chronic diseases|0https://id.loc.gov/authorities/subjects/
sh85025392|xTreatment.|0https://id.loc.gov/authorities/
subjects/sh99005040
650 0 Inflammation|xImmunological aspects.|0https://id.loc.gov/
authorities/subjects/sh86001714
650 0 Inflammation|0https://id.loc.gov/authorities/subjects/
sh85066108|xTreatment.|0https://id.loc.gov/authorities/
subjects/sh99005040
650 0 Mesenchymal Stromal Cells|xImmunology.
650 7 Chronic diseases|xTreatment.|2fast|0https://
id.worldcat.org/fast/860092
650 7 Chronic diseases.|2fast|0https://id.worldcat.org/fast/
860072
650 7 Inflammation|xImmunological aspects.|2fast|0https://
id.worldcat.org/fast/972435
650 7 Inflammation.|2fast|0https://id.worldcat.org/fast/972432
650 12 Mesenchymal Stem Cell Transplantation.|0https://
id.nlm.nih.gov/mesh/D045164
650 22 Chronic Disease|xtherapy.|0https://id.nlm.nih.gov/mesh/
D002908Q000628
650 22 Inflammation|ximmunology.|0https://id.nlm.nih.gov/mesh/
D007249Q000276
650 22 Inflammation|xtherapy.|0https://id.nlm.nih.gov/mesh/
D007249Q000628
650 22 Mesenchymal Stem Cells|ximmunology.|0https://
id.nlm.nih.gov/mesh/D059630Q000276
655 4 Electronic books.
700 1 Gross, Gerhard,|d1949-|0https://id.loc.gov/authorities/
names/n2013183552|eeditor.
700 1 Häupl, Thomas,|0https://id.loc.gov/authorities/names/
n2013183545|eeditor.
776 08 |iPrint version:|z9783110298260|z3110298260|w(DLC)
2013020145
856 40 |uhttps://rider.idm.oclc.org/login?url=http://
search.ebscohost.com/login.aspx?direct=true&scope=site&
db=nlebk&AN=661713|zOnline eBook. Access restricted to
current Rider University students, faculty, and staff.
856 42 |3Instructions for reading/downloading this eBook|uhttp://
guides.rider.edu/ebooks/ebsco
901 MARCIVE 20231220
948 |d20160607|cEBSCO|tebscoebooksacademic|lridw
994 92|bRID
