| Description |
1 online resource (331 pages) : illustrations (some color). |
|
text file |
| Series |
RSC drug discovery series ; no. 36
|
|
RSC drug discovery series ; 36.
|
| Summary |
This book will illustrate the successful partnership of chemistry and biology to advance successful biotherapeutic modalities. Molecular design to create function is common to both chemical and molecular biology, and this text will highlight recent developments from these disciplines that have delivered drugs, clinical candidates or significantly advanced biotherapeutic approaches. Biotherapeutics are often considered to be beyond the reach of the medicinal chemist, but this book demonstrates that chemistry has an essential role in the future success of this area, by explaining and describing the chemical biology technologies that underpin specific therapeutic advances and demonstrating the unique value of molecular design and understanding. Covering topics such as selective protein modification, immunopharmacotherapy, chemically programmed vaccinations, nanobodies and antibodies, this book will provide essential reading for medicinal and pharmaceutical chemists working in both industry and academia. |
| Bibliography |
Includes bibliographical references and index. |
| Contents |
Synthetic immunology -- Immunopharmacotherapy for nicotine addiction -- Carbohydrate vaccines -- Generation and maturation of therapeutic antibodies via in vitro somatic hypermutation -- Synthetic protein biologics -- Recent advances in antibody-drug conjugates -- MicroRNA biotherapeutics: key challenges from a drug development perspective -- Novel therapeutic agents from bacterial toxins -- Phage selection of mono- and bicyclic peptide ligands -- Chemical approaches for localization, characterization and mimicry of peptide epitopes -- Cystine-knot proteins. |
| Local Note |
eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America |
| Subject |
Biological products -- Therapeutic use.
|
|
Biological products -- Therapeutic use. |
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Biopharmaceutics. |
| Genre/Form |
Electronic books.
|
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Electronic books.
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| Added Author |
Jones, Lyn H., editor.
|
|
McKnight, Andrew J., editor.
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| Other Form: |
Print version: Biotherapeutics. Cambridge : Royal Society of Chemistry, 2013 9781849736015 (OCoLC)858826400 |
| ISBN |
9781849737159 (electronic book) |
|
1849737150 (electronic book) |
|
9781849736015 |
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1849736014 |
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