| Description |
1 online resource (129 pages). |
| Physical Medium |
polychrome |
| Description |
text file |
| Series |
Stem cells--laboratory and clinical research series
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Stem cells--laboratory and clinical research series.
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| Bibliography |
Includes bibliographical references and index. |
| Contents |
Preface; Chapter 1; Optimization of Adhesion Molecule Evaluation on In Vitro-Amplified Bone Marrow-Derived Mesenchymal Stromal Cells from Healthy Donors; Abstract; Abbreviations; Introduction; Materials and Methods; Experimental Design; Isolation and Expansion of Human MSCs from Bone Marrow (BM) Aspirates; EasySep Immunomagnetic Selection of STRO-1+ and STRO-1-/CD73+ hBM-MSCs; Cell Yield and Growth Kinetics of hBM-MSCs in a Culture System; Flow Cytometric Analysis of hBM-MSC Adhesion Molecule Expression; Statistical Analysis; Results |
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The Cell Yield and Growth Characteristics of the Three hBM-MSC Preparations Were Significantly DifferentThe In Vitro Adhesion Profile Was Different Depending on the hBM-MSC Preparation; The Variation in β1 Integrin Expression Significantly Correlated with hBM-MSC Proliferation; Discussion; Acknowledgments; References; Chapter 2; The Double Edged Sword of Adipose Derived Mesenchymal Stem/Stromal Cells in Cancer Therapy; Abstract; Introduction; A Dual Role for ASC in Mediating; or Inhibiting Tumor Promotion; The Interaction of ASC with Tumor Cells Can be Exploited for Therapy. |
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Uses of ASC for Inhibiting Tumor ProliferationThe Effect of ASC on Promoting Tumor Cell Proliferation; Angiogenesis Can Be Influenced by ASC-Mediated Signaling; Uses of ASC for Treating Tumor Angiogenesis; The Effects of ASC in Promoting Tumor Angiogenesis; ASC May Modulate Metastatic Ability of Dormant Tumor Cells; Uses of ASC for Preventing Tumor Cell Metastasis; The Effects of ASC in Promoting Tumor Cell Metastasis; ASC May Influence the Immune Response within the Tumor Microenvironment; Uses of ASC for Promoting an Immune-Mediated Anti-Tumor Response |
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The Effects of ASC in Promoting Tumorigenesis via Effects on the Immune SystemChallenges of ASC-Based Therapies: Tilting the Scale between Tumor Promotion and Inhibition; Conclusion; References; Chapter 3; Improving Clinical Uses of Mesenchymal Stromal Cells by 3D Scaffold-Free Constructs; Abstract; 1. Mesenchymal Stromal Cells; 1.1. MSCs Cell Suspension in Cell Therapy; Conclusion; 2. Top-Down Tissue Engineering; 2.1. Understanding Scaffolds in Cell and Tissue Microenvironment; Conclusion; 3. Scaffold-Free 3D Constructs in; Tissue Engineering |
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3.1. Technologies for Scaffold-Free 3D Construct Biofabrication3.2. MSCs Scaffold-Free 3D Constructs; Conclusion; 4. MSCs as Scaffold-Free 3D Constructs for Cell Delivery Improvement; 4.1. MSCs Spheroids in Bone Regeneration; 4.2. MSCs Spheroids in Cartilage Regeneration; 4.3. MSCs Spheroids for Ischemic Injuries Treatment; 4.4. MSCs Aggregates and Spheroids for Cardiac; Therapeutic Approaches; 4.5. MSCs Aggregates and Spheroids in Diabetic Wound Healing; Conclusion; 5. Bottom-Up Tissue Engineering; 5.1. What are Building-Blocks?; 5.1.1. Cell Sheets; 5.1.2. Cell-Laden Hydrogels |
| Local Note |
eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America |
| Subject |
Mesenchymal stem cells.
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Mesenchymal stem cells. |
| Genre/Form |
Electronic books.
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Electronic books.
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| Added Author |
Morrison, Randy, editor.
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| Other Form: |
Print version: Morrison, Randy Mesenchymal Stromal Cells (MSCs): Biology, Mechanisms of Action and Clinical Uses Hauppauge : Nova Science Publishers, Inc.,c2017 9781634856997 |
| ISBN |
9781634857208 (electronic book) |
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1634857208 (electronic book) |
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9781634856997 |
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