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Title An approach to evaluate the effects of concomitant prescribing of opioids and benzodiazepines on veteran deaths and suicides / Committee on Developing a Protocol to Evaluate the Concomitant Prescribing of Opioids and Benzodiazepine Medications and Veteran Deaths and Suicides, Board on Health Care Services, Health and Medicine Division.

Publication Info. Washington, DC : The National Academies Press, [2019]

Item Status

Description 1 online resource (1 PDF file (xii, 98 pages)) : color illustrations.
text file
Series A consensus study report of the National Academies of Sciences, Engineering, Medicine
Consensus study report.
Bibliography Includes bibliographical references.
Summary Introduction -- Specifying the target trial -- Observational emulation of the target trials and practical considerations.
"Opioid prescriptions for acute and chronic pain increased dramatically from the late 1990s into the current decade in both the civilian and the Department of Veterans Affairs and Department of Defense treatment environments. Similarly, prescriptions for benzodiazepines also increased significantly for anxiety and insomnia. Combinations of opioid and benzodiazepines have proben fatal when taken concurrently, with research demonstrating this phenomenon for nearly 40 years. This issue is exacerbated within the veteran population because of higher rates of pain, anxiety and other related health issues due to military life. An evaluation of the relationship between opioid and benzodiazepine medication practices at the VA is necessary to improve treatment for mental health and combat-related trauma for veterans. An Approach to Evaluate the Effects of Concomitant Prescribing of Opioids and Benzodiazepines on Veteran Deaths and Suicides investigates the effects of opioid initiation and tapering strategies in the presence of benzodiazepines in veterans. This report explores neurobiology and the principles of addiction and tolerance, in addition to the current use of opioids and benzodiazepines for treating pain and anxiety in both the veteran and general population. It also provides a protocol to evaluate the relationship between opioid and benzodiazepine medication practices. This framework is a critical foundation for further research to improve concomitant opioid and benzodiazepine medication practices for veterans and the general population"--Publisher's description.
Contents Summary -- Introduction -- Specifying the target trial -- Observational emulation of the target trials and practical considerations.
Local Note eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America
Subject Opioid abuse -- Prevention.
Opioid abuse.
Benzodiazepine abuse -- Prevention.
Benzodiazepine abuse.
Opioids -- Safety measures.
Opioids.
Industrial safety.
Benzodiazepines -- Safety measures.
Benzodiazepines -- Safety measures.
Benzodiazepines.
Veterans -- Medical care -- United States.
Veterans -- Medical care.
United States.
Veterans -- Suicidal behavior -- United States.
Veterans.
Suicidal behavior.
United States.
Genre/Form Electronic books.
Added Author National Academies of Sciences, Engineering, and Medicine (U.S.). Committee on Developing a Protocol to Evaluate the Concomitant Prescribing of Opioids and Benzodiazepine Medications and Veteran Deaths and Suicides, issuing body.
Other Form: Approach to evaluate the effects of concomitant prescribing of opioids and benzodiazepines on veteran deaths and suicides. [S.l.] : National Academies Press, 2019 0309495997 (OCoLC)1119765430
ISBN 9780309496001 (electronic book)
0309496004 (electronic book)
9780309496025 (electronic book)
0309496020 (electronic book)
0309495997 (paperback)
9780309495998 (paperback)