| Description |
1 online resource (1 PDF file (xvii, 407 pages)) : illustrations. |
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text file |
| Series |
A consensus study report of the National Academies of Sciences, Engineering, Medicine
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Consensus study report.
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| Bibliography |
Includes bibliographical references. |
| Summary |
Among the many who serve in the United States Armed Forces and who are deployed to distant locations around the world, myriad health threats are encountered. In addition to those associated with the disruption of their home life and potential for combat, they may face distinctive disease threats that are specific to the locations to which they are deployed. U.S. forces have been deployed many times over the years to areas in which malaria is endemic, including in parts of Afghanistan and Iraq. Department of Defense (DoD) policy requires that antimalarial drugs be issued and regimens adhered to for deployments to malaria-endemic areas. Policies directing which should be used as first and as second-line agents have evolved over time based on new data regarding adverse events or precautions for specific underlying health conditions, areas of deployment, and other operational factors At the request of the Veterans Administration, Assessment of Long-Term Health Effects of Antimalarial Drugs When Used for Prophylaxis assesses the scientific evidence regarding the potential for long-term health effects resulting from the use of antimalarial drugs that were approved by FDA or used by U.S. service members for malaria prophylaxis, with a focus on mefloquine, tafenoquine, and other antimalarial drugs that have been used by DoD in the past 25 years. This report offers conclusions based on available evidence regarding associations of persistent or latent adverse events. |
| Funding |
This activity was supported by Contract Order No. VA 36C24E18C0067 between the National Academy of Sciences and the Department of Veterans Affairs. Any opinions, findings, conclusions, or recommendations expressed in this publication do not necessarily reflect the views of any organization or agency that provided support for the project. |
| Contents |
Intro -- FrontMatter -- Reviewers -- Preface -- Contents -- Acronyms and Abbreviations -- Summary -- 1 Introduction -- 2 Background -- 3 Identification and Evaluation of the Evidence Base -- 4 Mefloquine -- 5 Tafenoquine -- 6 Atovaquone/Proguanil -- 7 Doxycycline -- 8 Primaquine -- 9 Chloroquine -- 10 Improving the Quality of Research on the Long-Term Health Effects of Antimalarial Drugs -- Appendix A: Public Meeting Agendas -- Appendix B: Invited Presentations -- Appendix C: Epidemiologic Studies That Met the Committee's Inclusion Criteria |
| Local Note |
eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America |
| Subject |
Malaria -- Evaluation.
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Malaria. |
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Evaluation. |
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Malaria -- Diagnosis.
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Malaria -- Diagnosis. |
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United States. |
| Genre/Form |
Systematic Review.
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Electronic books.
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Technical reports.
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Technical reports.
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| Added Author |
Savitz, David A., editor.
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Styka, Anne N., editor.
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National Academies of Sciences, Engineering, and Medicine (U.S.). Committee to Review Long-Term Health Effects of Antimalarial Drugs, issuing body.
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| Other Form: |
Print version: National Academies of Sciences, Engineering, and Medicine. Assessment of Long-Term Health Effects of Antimalarial Drugs When Used for Prophylaxis. Washington, D.C. : National Academies Press, ©2020 |
| ISBN |
9780309672115 |
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0309672112 |
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9780309672139 (electronic book) |
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0309672139 (electronic book) |
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9780309672108 (paperback) |
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0309672104 (paperback) |
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