| Description |
1 online resource (xii, 362 pages) : illustrations. |
| Physical Medium |
polychrome |
| Description |
text file |
| Series |
Biology of extracellular matrix series
|
|
Biology of extracellular matrix.
|
| Bibliography |
Includes bibliographical references and index. |
| Contents |
The matrix metalloproteinase family / J. Frederick Woessner, Jr. -- Interstitial collagenases / John J. Jeffrey -- Stromelysins 1 and 2 / Hideaki Nagase -- 72-kDa gelatinase (gelatinase A) : structure, activation, regulation, and substrate specificity / Anita E. Yu, Anne N. Murphy, and William G. Stetler-Stevenson -- Gelatinase B : structure, regulation, and function / Thiennu H. Vu and Zena Werb -- Matrilysin / Carole L. Wilson and Lynn M. Matrisian -- Macrophage elastase (MMP-12) / Steven D. Shapiro and Robert M. Senior -- Membrane-type matrix metalloproteinases and cell surface-associated activation cascades for matrix metalloproteinases / Vera Knäuper and Gillian Murphy -- Substrate specificity and mechanisms of substrate recognition of the matrix metalloproteinases / Vera Imper and Harold E. Van Wart -- Synthetic inhibitors of matrix metalloproteinases / Peter D. Brown -- Matrix metalloproteinases in tissue repair / William C. Parks [and others] -- Regulation of matrix metalloproteinase gene expression / M. Elizabeth Fini [and others]. |
| Summary |
The chapters in this book thoroughly cover the structure, regulation, and function of matrix metalloproteinases, and provide information on the latest strategies to inhibit enzyme activity. This work will be an indispensable reference tool for investigators with an interest in extracellular matrix biology, matrix turnover, enzymology and biochemistry of proteinases, developmental biology, pathology, and therapeutic interventions. Key Features * Provides state-of-the-art information on a field with broad implications to many areas of biology * Includes detailed coverage of the structure and regulation of all major matrix metalloproteinases * Chapters focus on a timely and expanding field * Topics have direct relevance to understanding human disease pathology of cancer, arthritis, and vascular disease * Discusses latest strategies used in the development of new therapeutics to inhibit metalloproteinase activity. |
| Local Note |
eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America |
| Subject |
Metalloproteinases.
|
|
Metalloproteinases. |
|
Extracellular matrix proteins.
|
|
Extracellular matrix proteins. |
|
Metalloendopeptidases. |
|
Extracellular Matrix -- enzymology. |
| Genre/Form |
Electronic books.
|
| Added Author |
Parks, William C.
|
|
Mecham, Robert P.
|
| Other Form: |
Print version: Matrix metalloproteinases. San Diego : Academic Press, ©1998 0125450907 9780125450904 (DLC) 98133584 (OCoLC)38845311 |
| ISBN |
9780125450904 |
|
0125450907 |
|
9780080535982 (electronic book) |
|
0080535984 (electronic book) |
|
1281057045 |
|
9781281057044 |
|
