LEADER 00000cam a2200661Ii 4500 
001    ocn947837588 
003    OCoLC 
005    20180130100425.3 
006    m     o  d         
007    cr cnu|||unuuu 
008    160426s2016    nyu     ob    001 0 eng d 
020    9781634847957|qelectronic book 
020    1634847954|qelectronic book 
020    |z9781634847810 
035    (OCoLC)947837588 
040    N$T|beng|erda|epn|cN$T|dN$T|dOCLCF|dYDXCP|dEBLCP 
049    RIDW 
050  4 RC643 
072  7 HEA|x039000|2bisacsh 
072  7 MED|x014000|2bisacsh 
072  7 MED|x022000|2bisacsh 
072  7 MED|x112000|2bisacsh 
072  7 MED|x045000|2bisacsh 
082 04 616.99419|223 
090    RC643 
245 00 Diversity, versatility and leukaemia /|cGeoffrey Brown, 
       Isidro Sanchez-Garcia. 
264  1 New York :|bNova Science Publishers, Inc.,|c[2016] 
264  4 |c©2016 
300    1 online resource. 
336    text|btxt|2rdacontent 
337    computer|bc|2rdamedia 
338    online resource|bcr|2rdacarrier 
340    |gpolychrome|2rdacc 
347    text file|2rdaft 
490 1  cancer etiology, diagnosis and treatments 
504    Includes bibliographical references and index. 
505 0  DIVERSITY, VERSATILITY AND LEUKAEMIA ; DIVERSITY, 
       VERSATILITY AND LEUKAEMIA ; Library of Congress Cataloging
       -in-Publication Data; Contents ; Preface; Short Abstract; 
       Acknowledgments; Chapter 1 The Diversity of Blood Cells ; 
       Introduction; Red and Colourless Corpuscles; The Various 
       Major Blood and Immune Cell Types; Innate Immune Cells -- 
       The Immediate Line of Defence; The Adaptive Immune System;
       Delineating Cell Lineages; Conclusion; References; Chapter
       2 The Conventional Viewpoint to Hematopoiesis Introduction
       ; The Nature of Haematopoietic Stem Cells 
505 8  Compartmentalisation of Developing Blood CellsTwo Families
       of Cells; A Single and Preferred Route to a Particular 
       Cell Fate; Conclusion; References; Chapter 3 Revision to 
       the Model of Haematopoiesis ; Introduction; Is There Just 
       a Single Family of Blood Cells?; The True Nature of 
       Haematopoietic Stem Cells; The Versatility of 
       Developmental Pathways; Revising the Classic Model for 
       Haematopoiesis; The Instructive Action of Haematopoietic 
       Growth Factors; Conclusion; References; Chapter 4 
       Classifying the Various Leukaemias/Haematopoietic Cancers 
       ; Introduction 
505 8  Classification of Leukaemias/Haematopoietic Cancers Based 
       on Histology and Cytological FeaturesImmunophenotype- and 
       Genetic Abnormalities-Based Classifications of Leukaemias/
       Haematopoietic Cancers: Assignment of Human Haematopoietic
       Malignancy to Their Normal Cell Counterparts; 
       Classification of Leukaemias/Haematopoietic Cancers Using 
       New Technologies; Classification Using Gene Expression 
       Profiling; Classification Using Next Generation 
       Sequencing; Conclusion; References; Chapter 5 Leukaemia/
       Haematopoietic Cancer-Initiating Cellular Events ; 
       Introduction; Treating Cancer 
505 8  The Relevance of Oncogenes in Human CancerThe Influence of
       Oncogenes on Their Target Cell; The Cancer Stem Cell 
       Theory; The Nature of the Cancer Cell-of-Origin; 
       Conclusion; References; Chapter 6 Leukaemia/Haematopoietic
       Cancers and Lineage Commitment ; Introduction; The Concept
       of Cellular Reprogramming; Experimental Models of Tumoral 
       Reprogramming; Tumoral Reprogramming: Therapeutic 
       Evidences; P53 Is a Barrier to Tumoral Stem Cell 
       Reprogramming; Fidelity of Tumour Lineage Conversion by 
       Oncogenes and Epigenetic Memory; Conclusion; References 
505 8  Chapter 7 The Prospect of New Treatments for Leukaemia and
       Other Cancers Introduction; Biology and the Treatment of 
       Cancer; The Current Paradigm in Cancer Treatment; A New 
       Paradigm: Cancer Stem Cells; Practical Implications of the
       CSC Hypothesis; The Nature of Epigenetic Signatures within
       Cells; Current Use of Epigenetic Modulators to Treat 
       Cancer; Conclusion; References; Authors' Contact 
       Information; Index 
588 0  Vendor-supplied metadata. 
590    eBooks on EBSCOhost|bEBSCO eBook Subscription Academic 
       Collection - North America 
650  0 Leukemia.|0https://id.loc.gov/authorities/subjects/
       sh85076285 
650  0 Blood cells.|0https://id.loc.gov/authorities/subjects/
       sh85014968 
650  7 Leukemia.|2fast|0https://id.worldcat.org/fast/996894 
650  7 Blood cells.|2fast|0https://id.worldcat.org/fast/834680 
655  4 Electronic books. 
700 1  Brown, Geoffrey,|d1963-|0https://id.loc.gov/authorities/
       names/n2009181778|eauthor. 
700 1  Sánchez-García, Isidro,|0https://id.loc.gov/authorities/
       names/n2017056350|eauthor. 
830  0 Cancer etiology, diagnosis, and treatments.|0https://
       id.loc.gov/authorities/names/n2009183163 
856 40 |uhttps://rider.idm.oclc.org/login?url=http://
       search.ebscohost.com/login.aspx?direct=true&scope=site&
       db=nlebk&AN=1226195|zOnline eBook. Access restricted to 
       current Rider University students, faculty, and staff. 
856 42 |3Instructions for reading/downloading the EBSCO version 
       of this eBook|uhttp://guides.rider.edu/ebooks/ebsco 
901    MARCIVE 20231220 
948    |d20180209|cEBSCO|tEBSCOebooksacademic NEW 1-29-18|lridw 
994    92|bRID