| Description |
1 online resource (193 pages) : illustrations. |
|
text file |
| Series |
Molecular biology intelligence unit
|
|
Molecular biology intelligence unit (Unnumbered)
|
| Bibliography |
Includes bibliographical references and index. |
| Contents |
Front Cover; The SV40 Replicon Model for Analysis of Anticancer Drugs; Copyright Page; Contents; Chapter 1. Papovavirus Models for Mammalian Replicons; Chapter 2. Analysis of SV40 DNA Replication Intermediates; Chapter 3. Catastrophic Failure of DNA Replication Forks: Structural and Recombinational Pathways; Chapter 4. Topoisomerase II and Termination of DNA Replication; Chapter 5. DNA Damaging Agents; Chapter 6. Drug Discovery and Evaluation with SV40; Chapter 7. SV40 In Vitro DNA Replication: A Potential Model For Studying Anticancer Drug Action. |
| Summary |
This book provides the most up-to-date review of the simian virus 40 (SV40) minichromosome as a model for the mammalian chromosome in studies of DNA replication. It focuses on disruption of DNA replication by anticancer drugs and DNA-damaging agents. There is a strong emphasis on the unique advantages of SV40 as an experimental system for the analysis of these classes of anticancer drug mechanisms. The new high-resolution gel electrophoresis methods for the analysis of SV40 DNA replication are covered in detail to aid readers in designing and interpreting similar experiments. |
| Local Note |
eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America |
| Subject |
SV40 (Virus)
|
|
SV40 (Virus) |
|
Viral genetics.
|
|
Viral genetics. |
|
Antineoplastic agents -- Research -- Methodology.
|
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Antineoplastic agents -- Research. |
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Methodology. |
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Antineoplastic agents. |
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DNA-drug interactions.
|
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DNA-drug interactions. |
|
Simian virus 40 -- drug effects. |
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Simian virus 40 -- genetics. |
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DNA Replication -- drug effects. |
|
Models, Genetic. |
| Genre/Form |
Electronic books.
|
|
Repliken.
|
| Other Form: |
Print version: Snapka, Robert M., 1947- SV40 replicon model for analysis of anticancer drugs. [San Diego, Calif.] : Academic Press ; Austin, TX : R.G. Landes, ©1996 (DLC) 96000579 (OCoLC)34121051 |
| ISBN |
9780080550183 (electronic book) |
|
0080550185 (electronic book) |
|
1281018910 |
|
9781281018915 |
|
0126536309 |
|
9780126536300 |
|
0412105217 (alkaline paper) |
|
9780412105210 (alkaline paper) |
|
