| Description |
1 online resource (xviii, 265 pages) : illustrations (some color) |
| Physical Medium |
polychrome |
| Description |
text file |
| Bibliography |
Includes bibliographical references and index. |
| Contents |
The drug discovery crisis -- A new science of molecules -- The birth of the first cancer drugs -- A new company creating drug combinations -- The undruggable RAS protein -- The druggable genome -- Peering inside proteins -- The nature of interactions between proteins -- From protein-protein interactions to personalized medicines -- A revolution in peptide synthesis -- A vast array of drug candidates -- Moving outside the small molecule box -- Accelerating the arrival of next-generation drugs. |
| Summary |
After more than fifty years of blockbuster drug development, skeptics are beginning to fear we may be reaching the end of drug discovery to combat major diseases. In this engaging book, Brent Stockwell, a leading researcher in the exciting new science of chemical biology, describes this dilemma and the powerful techniques that may bring drug research into the twenty-first century. Filled with absorbing stories of breakthroughs, the book begins with the scientific achievements of the twentieth century that led to today's drug innovations. We learn how the invention of mustard gas in. |
| Local Note |
eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America |
| Subject |
Drug development.
|
|
Drug development. |
|
Drugs -- Design.
|
|
Drugs -- Design. |
|
Proteins -- Metabolism.
|
|
Proteins -- Metabolism. |
|
Drug Discovery -- methods. |
|
Drug Design. |
|
Proteins -- chemistry. |
|
Proteins -- metabolism. |
| Genre/Form |
Electronic books.
|
| Subject |
Medication. |
| Other Form: |
Print version: Stockwell, Brent R. Quest for the cure. New York : Columbia University Press, ©2011 (DLC) 2010053573 |
| ISBN |
9780231525527 (electronic book) |
|
0231525524 (electronic book) |
|
9780231152129 |
|
0231152124 |
|
1283072777 |
|
9781283072779 |
|
