| Description |
1 online resource (338 pages) |
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text file |
| Contents |
FOREWORD ; PREFACE ; List of Contributors ; Stem Cells in Hematopoietic Processes and Therapy Tools ; HEMATOPOIETIC STEM CELLS (HSCS); Hematopoiesis ; The Discovery of Hematopoietic Stem Cells (HSCs); The Identification of HSCs ; BIOLOGICAL REGULATION OF HEMATOPOIETIC STEM CELLS; HSC Niche; Molecular Pathways in HSC Regulation; PI3K Signaling Pathway; mTOR; Protein Tyrosine Phosphatase Shp2; Ubiquitin Proteasome System; Transcription Regulators ; THERAPEUTIC APPLICATION OF HSCS; Hematopoietic Cell Transplantation (HCT) (or Bone Marrow Transplantation); HCT and Immuno-Diseases. |
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Drawbacks of HCT TransplantationOrgan Transplantation; Viral Infection; HSC Gene Therapy ; HSC Gene Therapy for SCID-X1; HSC Gene Therapy for ADA-SCID; HSC Gene Therapy for β-Thalassemia; iPSC-based Hematologic Disease Treatment; iPSCs in Blood Diseases; Potential of iPSCs in Drug Development; Summary; CONFLICT OF INTEREST; ACKNOWLEDGEMENTS; REFERENCES; Epithelial Oral Stem Cells ; INTRODUCTION; Genetic Labeling; Clone Formation; Stem Cell Markers; Location of Oral Epithelial Stem Cells; Stem Cell Niche; Cancer Stem Cells (CSC); The Origin of Cancer Cells; CSC Provenience; CSC Identification. |
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CD44 ALDH; CD133; Oct-4, Sox2 and Nanog; c-Met; Side Populations (SPs) ; Cancer Stem Cell Niche; Treatment Resistance of CSC; Oral Stem Cells in Regeneration; CONCLUSIVE REMARKS; CONFLICT OF INTEREST; ACKNOWLEDGEMENTS; REFFERENCES; Skin Stem Cells in Cutaneous Wound Healing and Tumorigenesis ; INTRODUCTION; Interfollicular Epidermal Stem Cells; Hair Follicle Stem Cells; Stem Cells of Sebaceous Glands; Stem Cells of Sweat Glands; Dermal Stem Cells; SKIN STEM CELLS IN REGENERATION AND WOUND HEALING; Inflammatory Phase; Proliferative Phase; Remodeling Phase; LINKING REGENERATION TO TUMORIGENESIS. |
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CANCER STEM CELL -- MAJOR PLAYER IN SKIN TUMORIGENESISMechanisms that Generate Non-Melanoma Skin Cancer; Stem Cells: at the Root of Human Skin Carcinomas; Skin Cancer Microenvironment; Stem Cells as Triggers Of Tumorigenesis in BCC; Stem Cells and Wound-Induced Tumors ; Perturbation of Stem Cell Behavior in BCC; Stem Cell -Related Tumorigenesis in SCC; Two-Stage Skin Carcinogenesis Mouse Model -- Clues for Cancer Stem Cells Involvement in SCC Initiation; Potential Role of Cancer Stem Cells in Melanoma -- Still a Matter of Debate; CONCLUSIVE REMARKS; CONFLICT OF INTEREST; ACKNOWLEDGEMENTS. |
| Bibliography |
REFERENCESStem Cells in Neurodegeneration ; INTRODUCTION; NEURAL STEM CELL NICHE ORGANIZATION IN ADULT MAMMALIAN BRAIN ; MAINTENANCE OF NEURAL STEM CELL NICHE IN THE OLD BRAIN; NEUROREGENERATION RESERVE IN NEURODEGENERATIVE DISEASES; USE OF STEM CELLS AS THERAPEUTIC APPROACHES IN NEURODEGENERATIVE DISORDERS; Neuronal Stem Cells and Committed Progenitors-Based Therapies; Induced Pluripotent Stem Cells Based Therapies; Mesenchymal Stem Cell Based Therapies; Cell-Free Extracts of Stem Cells as Alternative Therapy to Stem Cell Transplant in Neurodegenerative Diseases; CONCLUSION. |
| Note |
CONFLICT OF INTEREST. |
| Local Note |
eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America |
| Subject |
Stem cells -- Therapeutic use.
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Stem cells. |
| Genre/Form |
Electronic books.
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| Added Author |
Neagu, Monica.
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| Other Form: |
Print version: Tanase, Cristiana. Stem Cells Between Regeneration and Tumorigenesis. Sharjah : Bentham Science Publishers, ©2016 9781681083322 |
| ISBN |
9781681083315 (electronic book) |
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1681083310 (electronic book) |
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