Title In vitro and in vivo development of a topical drug for the treatment of equine skin cancer - based on naturally occurring and synthetically modified substances in plane bark.

Publication Info.

Göttingen : Cuvillier Verlag, 2021.

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Online ebook via EBSCO. Access restricted to current Rider University students, faculty, and staff.
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Description	1 online resource (141 pages).
Physical Medium	polychrome
Description	text file
Series	Wissenschaftliche Reihe der Klinik für Pferde ; v.51
	Wissenschaftliche Reihe der Klinik für Pferde.
Note	Description based upon print version of record.
Contents	Intro -- LIST OF ABBREVIATIONS -- SUMMARY -- ZUSAMMENFASSUNG -- 1. Introduction -- 1.1. The equine malignant melanoma -- 1.2. The equine sarcoid: an overview -- 1.3. Topical drug application -- 1.4. Naturally occurring substances in plane bark and their syntheticallymodified derivatives -- 1.5. Hypotheses and aims of the thesis -- 2. Manuscript I:Betulinic acid shows anticancer activity against equine melanoma cells andpermeates isolated equine skin in vitro -- 2.1. Supplemental data
	3. Manuscript II:In vitro assessment of triterpenoids NVX-207 and betulinyl-bis-sulfamate asa topical treatment for equine skin cancer -- 4. Manuscript III:Concentration profiles and safety of topically applied betulinic acid andNVX-207 in eight healthy horses -- A randomized, blinded, placebocontrolled,crossover pilot study -- 5. Manuscript IV:Effects of topically applied betulinic acid and NVX-207 on early stageequine melanoma -- A prospective, randomized, double-blind, placebocontrolledpilot study -- 6. General discussion -- 6.1. Summarized findings -- 6.2. Interpretation of the findings
	7. Major findings and conclusions -- 8. Future perspectives -- 9. References -- Affidavit -- Acknowledgements
Local Note	eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America
Subject	Horses -- Diseases.
	Horses -- Diseases.
	Skin -- Cancer.
	Skin -- Cancer.
	Bark.
	Bark.
Genre/Form	Electronic books.
Other Form:	Print version: Weber, Lisa Annabel In vitro and in vivo development of a topical drug for the treatment of equine skin cancer - based on naturally occurring and synthetically modified substances in plane bark Göttingen : Cuvillier Verlag,c2021 9783736974326
ISBN	3736964323
	9783736964327 (electronic book)

Title In vitro and in vivo development of a topical drug for the treatment of equine skin cancer - based on naturally occurring and synthetically modified substances in plane bark.

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