| Description |
1 online resource (ix, 390 pages) : illustrations (some color) |
| Physical Medium |
polychrome |
| Description |
text file |
| Bibliography |
Includes bibliographical references and index. |
| Contents |
X-ray study of protein-protein complexes and analysis of interfaces / Joel Janin -- A structural perspective on protein-protein interactions in macromolecular assemblies / Ranjit P. Bahadur -- Energetics of protein-protein interactions / Ilian Jelesarov -- Kinetics of biomacromolecular complex formation: theory and experiment / Georgi V. Pachov, Razif R. Gabdoulline and Rebecca C. Wade -- Evolutionary trace of protein functional determinants / Olivier Lichtarge -- Protein-protein docking / Adrien Saladin and Chantal Prevost -- Data-driven docking: using external information to spark the biomolecular rendez-vous / Adrien S.J. Melquiond and Alexandre M.J.J. Bonvin -- High-resolution protein-protein docking / Nir London and Ora Schueler-Furman -- Scoring and refinement of predicted protein-protein complexes / Martin Zacharias -- Motif-mediated protein interactions and their role in disease / Holger Dinkel and Heinrich Sticht -- Prediction and calculation of protein-protein binding affinities and mutation effects / Sébastien Fiorucci, Serge Antonczak and Jérôme Golebiowski -- Small-molecule inhibitors of protein-protein interactions / Thorsten Berg -- Protein dynamics and drug design: the role of molecular simulations / Giulia Morra, Alessandro Genoni and Giorgio Colombo. |
| Summary |
Given the immense progress achieved in elucidating protein-protein complex structures and in the field of protein interaction modeling, there is great demand for a book that gives interested researchers/students a comprehensive overview of the field. This book does just that. It focuses on what can be learned about protein-protein interactions from the analysis of protein-protein complex structures and interfaces. What are the driving forces for protein-protein association? How can we extract the mechanism of specific recognition from studying protein-protein interfaces? How can this knowledge. |
| Local Note |
eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America |
| Subject |
Protein-protein interactions.
|
|
Protein-protein interactions. |
|
Multiprotein Complexes -- chemistry. |
|
Protein Interaction Mapping. |
|
Protein Binding. |
|
Protein Conformation. |
| Genre/Form |
Electronic books.
|
| Added Author |
Zacharias, Martin.
|
| Other Form: |
Print version: Protein-protein complexes. London : Imperial College Press ; Singapore ; Hackensack, NJ : Distributed by World Scientific Pub. Co., ©2010 9781848163386 (OCoLC)619653723 |
| ISBN |
9781848163409 (electronic book) |
|
1848163401 (electronic book) |
|
9781848163386 |
|
184816338X |
|
9781848163393 |
|
1848163398 |
| Standard No. |
9786612759840 |
|
