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LEADER 00000cam a2200625 i 4500 
001    ocn952571190 
003    OCoLC 
005    20230113054233.0 
006    m     o  d         
007    cr cnu|||unuuu 
008    160630s2016    sz      o     000 0 eng d 
019    1059009147 
020    9783319312514|q(electronic book) 
020    3319312510|q(electronic book) 
020    3319312499|q(print) 
020    9783319312491|q(print) 
020    |z9783319312491|q(print) 
024 7  10.1007/978-3-319-31251-4|2doi 
035    (OCoLC)952571190|z(OCoLC)1059009147 
040    N$T|beng|erda|epn|cN$T|dGW5XE|dIDEBK|dN$T|dYDXCP|dUPM
       |dOCLCF|dCOO|dJG0|dUAB|dOCLCQ|dIAD|dJBG|dICW|dZ5A|dILO
       |dICN|dOCLCQ|dESU|dIOG|dU3W|dREB|dWYU|dOCLCO|dOCLCA|dMERER
       |dOCLCO|dOCLCA|dAUD|dOCLCO|dOCLCQ|dUKAHL|dAJS|dOCLCA|dNLW
       |dOCLCO|dOCLCQ 
049    RIDW 
050  4 QP114.C44 
072  7 MED|x085000|2bisacsh 
082 04 617.9/54|223 
090    QP114.C44 
245 00 Cardiomyocytes -- active players in cardiac disease /
       |cKlaus-Dieter Schlüter, editor. 
264  1 Switzerland :|bSpringer,|c2016. 
300    1 online resource 
336    text|btxt|2rdacontent 
337    computer|bc|2rdamedia 
338    online resource|bcr|2rdacarrier 
340    |gpolychrome|2rdacc 
347    text file|2rdaft 
505 0  Cardiomyocytes: Function and Regeneration -- 1. Ways to 
       study the biology of cardiomyocytes -- 2. Cardiomyocytes: 
       Function and Regeneration -- 3. Excitation-contraction 
       coupling of cardiomyocytes -- 4. Cardiac metabolism and 
       energetic control -- 5. Endogenous mechanisms for 
       regulating myocardial contractility -- Cardiomyocytes in 
       ageing, disease, and protection -- 6. Growth regulation of
       cardiomyocytes: Control of cell size and its role in 
       cardiac hypertrophy -- 7. Protein Degradation in 
       Cardiomyocytes? Target Proteins and clinical consequences 
       -- 8. Ischemia and Reperfusion -- 9. Mechanisms of cardiac
       cell death -- 10. Oxidative stress and nitrosative stress.
520    This book summarizes our current understanding about the 
       biology and patho-biology of cardiomyocytes and depicts 
       common techniques for the study of these cells. The book 
       is divided into two parts; the first part provides insight
       into role and function of cardiomyocytes under normal 
       conditions and describes embryogenesis and differentiation,
       in the second part the role of cardiomyocytes in aging and
       disease is discussed and cellular responses under stress 
       conditions illustrated. Cardiomyocytes represent the main 
       mass of the heart, and cellular malfunction directly 
       modifies heart function leading to subsequent heart 
       failure. As such, cardiomyocytes are causative involved in
       the main reasons of heart failure, such as post-infarct 
       remodeling, hypertensive heart disease, idiopathic heart 
       failure, and interactions with other co-morbidities such 
       as diabetes. On the other hand, cardiomyocytes are 
       necessarily target of therapy. Therefore, a precise 
       understanding of cardiomyocytes biology is a pre-requisite
       for proper disease treatment and evidence based medicine. 
       The book is written for cell biologists, pharmacologists 
       and biomedical researchers specialized in cardiac and 
       vascular biology. 
588 0  Online resource; title from PDF title page (SpringerLink, 
       viewed July 7, 2016). 
590    eBooks on EBSCOhost|bEBSCO eBook Subscription Academic 
       Collection - North America 
650  0 Heart cells.|0https://id.loc.gov/authorities/subjects/
       sh87004510 
650  0 Heart|xDiseases|xMolecular aspects.|0https://id.loc.gov/
       authorities/subjects/sh89006611 
650  7 Heart cells.|2fast|0https://id.worldcat.org/fast/953714 
650  7 Heart|xDiseases|xMolecular aspects.|2fast|0https://
       id.worldcat.org/fast/953545 
650  7 Cardiovascular medicine.|2bicssc 
650  7 Physiology.|2bicssc 
650  7 Pharmaceutical technology.|2bicssc 
650  7 Cellular biology (cytology)|2bicssc 
650  7 MEDICAL|xSurgery|xGeneral.|2bisacsh 
700 1  Schlüter, Klaus-Dieter,|0https://id.loc.gov/authorities/
       names/n2016188675|eeditor. 
776 08 |iPrinted edition:|z9783319312491 
856 40 |uhttps://rider.idm.oclc.org/login?url=https://
       search.ebscohost.com/login.aspx?direct=true&scope=site&
       db=nlebk&AN=1181928|zOnline ebook via EBSCO. Access 
       restricted to current Rider University students, faculty, 
       and staff. 
856 42 |3Instructions for reading/downloading the EBSCO version 
       of this ebook|uhttp://guides.rider.edu/ebooks/ebsco 
901    MARCIVE 20231220 
948    |d20230203|cEBSCO|tEBSCOebooksacademic NEW 6073 Quarterly
       |lridw 
994    92|bRID