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Bestseller
BestsellerE-book
Author Gunton, J. D. (James D.), 1937-

Title Protein condensation : kinetic pathways to crystallization and disease / J.D. Gunton, A. Shiryayev, and D.L. Pagan.

Publication Info. Cambridge, UK ; New York, N.Y. : Cambridge University Press, 2007.

Item Status

Description 1 online resource (xii, 364 pages) : illustrations
Physical Medium polychrome
Description text file
Bibliography Includes bibliographical references and index.
Summary The quest to understand the condensation of proteins from solutions is a rapidly evolving field. The purpose of this book is to bring to an interdisciplinary audience the state-of-the-art in current research. The first part of the book deals with issues related to the production of high quality protein crystals from solution. Since protein function is determined by structure, high quality protein crystals must be grown in order to determine their structure by X-ray crystallography. The book also discusses diseases that occur due to undesired protein condensation, an increasingly important subject. Examples include sickle cell anemia, cataracts and Alzheimer's disease. Current experimental and theoretical work on these diseases is discussed, which seeks understanding at a fundamental, molecular level, to prevent the undesired condensation from occurring. The book, containing color plate sections, is suitable for graduate students and academic researchers in physics, chemistry, structural biology, protein crystallography and medicine.
Contents Globular protein structure -- Experimental methods -- Thermodynamics and statistical mechanics -- Protein-protein interactions -- Theoretical studies of equilibrium -- Nucleation theory -- Experimental studies of nucleation -- Lysozyme -- Some other globular proteins -- Membrane proteins -- Crystallins and cataracts -- Sickle hemoglobin and sickle cell anemia -- Alzheimer's disease.
Local Note eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America
Subject Proteins.
Proteins.
Condensation.
Condensation.
Genre/Form Electronic book.
Electronic books.
Added Author Shiryayev, A. (Andrey)
Pagan, D. L. (Daniel L.)
Other Form: Print version: Gunton, J.D. (James D.), 1937- Protein condensation. Cambridge, UK ; New York, N.Y. : Cambridge University Press, 2007 9780521851213 0521851211 (OCoLC)144225234
ISBN 9780511342820 (electronic book)
0511342829 (electronic book)
0511341199
9780511341199
0511342292 (electronic book)
9780511342295 (electronic book)
1281085383
9781281085382
9780511535321 (ebook)
0511535325 (ebook)
0521851211 (Cloth)
9780521851213
Standard No. 9786611085384