LEADER 00000cam a2200709Ia 4500
001 ocn319518109
003 OCoLC
005 20160527041334.4
006 m o d
007 cr cn|||||||||
008 090428s2008 enka ob 001 0 eng d
019 244445013|a506353085|a671957806
020 9781847558282|q(electronic book)
020 1847558283|q(electronic book)
020 0854042571|q(hardback)
020 9780854042579|q(hardback)
020 |z9780854042579
035 (OCoLC)319518109|z(OCoLC)244445013|z(OCoLC)506353085
|z(OCoLC)671957806
037 T2869|bRoyal Society of Chemistry|nhttp://www.rsc.org/spr
040 UKRSC|beng|epn|cUKRSC|dUKRSC|dOKU|dCUS|dE7B|dOCLCQ|dN$T
|dOCLCF|dNLGGC|dCOO|dYDXCP|dDEBSZ|dCBT|dU5D|dOCLCQ
049 RIDW
050 4 QP551|b.P69582133 2008
070 QP551|b.P69582133 2008
072 7 SCI|x007000|2bisacsh
072 7 PSBC|2bicssc
072 7 PNRW|2bicssc
072 7 PNFL2|2bicssc
072 7 SCI|2eflch
082 04 572.6|222
090 QP551|b.P69582133 2008
245 00 Protein folding, misfolding and aggregation :|bclassical
themes and novel approaches /|cedited by Victor Muñoz.
264 1 Cambridge, UK :|bRoyal Society of Chemistry,|c[2008]
264 4 |c©2008
300 1 online resource (xv, 272 pages) :|billustrations (some
color).
336 text|btxt|2rdacontent
337 computer|bc|2rdamedia
338 volume|bnc|2rdacarrier
340 |gpolychrome|2rdacc
347 text file|2rdaft
490 1 RSC biomolecular sciences
504 Includes bibliographical references and index.
505 0 The [alpha]-helix as the simplest protein model : helix-
coil theory, stability, and design -- Kinetics and
mechanisms of [alpha]-helix formation -- The protein
folding energy landscape : a primer -- Hydrogen exchange
experiments : detection and characterization of protein
folding intermediates -- Statistical differential scanning
calorimetry : probing protein folding-unfolding ensembles
-- Fast protein folding -- Single molecule spectroscopy in
protein folding: from ensembles to single molecules --
Computer simulations of protein folding -- Protein design
: tailoring sequence, structure, and folding properties --
Protein misfolding and [beta]-amyloid formation --
Scenarios for protein aggregation : molecular dynamics
simulations and bioinformatics analysis.
520 This unique book covers all the modern approaches and the
many advances experienced in the field of protein folding
and aggregation during the last 10 years.|bProtein folding
and aggregation is the process by which newly synthesized
proteins fold into the specific three-dimensional
structures defining their biologically active states. It
has always been a major focus of research in biochemistry
and has often been seen as the unsolved second part of the
genetic code. In the last 10 years we have witnessed a
quantum leap in the research in this exciting area.
Computational methods have improved to the extent of
making possible to simulate the complete folding process
of small proteins and the early stages of protein
aggregation. Experimental methods have evolved to permit
resolving fast processes of folding reactions and
visualizing single molecules during folding. The findings
from these novel experiments and detailed computer
simulations have confirmed the main predictions of
analytical theory of protein folding. In summary, protein
folding research has finally acquired the status of a
truly quantitative science, paving the way for more
exciting developments in the near future. This unique book
covers all the modern approaches and the many advances
experienced in the field during the last 10 years. There
is also much emphasis on computational methods and studies
of protein aggregation which have really flourished in the
last decade. It includes chapters in the areas that have
witnessed major developments and are written by top
experts including:computer simulations of folding, fast
folding, single molecule spectroscopy, protein design,
aggregation studies (both computational and experimental).
Readers will obtain a unique perspective of the problems
faced in the biophysical study of protein conformational
behaviour in aqueous solution and how these problems are
being solved with a multidisciplinary approach that
combines theory, experiment and computer simulations.
Protein Folding, Misfolding and Aggregation Classical
Themes and Novel Approaches is essential reading for
graduate students actively involved in protein folding
research, other scientists interested in the recent
progress of the field and instructors revamping the
protein folding section of their biochemistry and
biophysics courses.
588 0 Print version record.
590 eBooks on EBSCOhost|bEBSCO eBook Subscription Academic
Collection - North America
650 0 Protein folding.|0https://id.loc.gov/authorities/subjects/
sh89006334
650 0 Proteins|xDenaturation.|0https://id.loc.gov/authorities/
subjects/sh85107670
650 2 Protein Folding.|0https://id.nlm.nih.gov/mesh/D017510
650 2 Protein Denaturation.|0https://id.nlm.nih.gov/mesh/D011489
650 7 Protein folding.|2fast|0https://id.worldcat.org/fast/
1079687
650 7 Proteins|xDenaturation.|2fast|0https://id.worldcat.org/
fast/1079732
655 4 Electronic books.
700 1 Muñoz, Victor,|d1965-|0https://id.loc.gov/authorities/
names/no2008124175
776 08 |iPrint version:|tProtein folding, misfolding and
aggregation.|dCambridge, UK : Royal Society of Chemistry,
©2008|z9780854042579|z0854042571|w(DLC) 2008298649
|w(OCoLC)192055856
830 0 RSC biomolecular sciences.|0https://id.loc.gov/authorities
/names/n2006182099
856 40 |uhttps://rider.idm.oclc.org/login?url=http://
search.ebscohost.com/login.aspx?direct=true&scope=site&
db=nlebk&AN=496913|zOnline eBook. Access restricted to
current Rider University students, faculty, and staff.
856 42 |3Instructions for reading/downloading this eBook|uhttp://
guides.rider.edu/ebooks/ebsco
901 MARCIVE 20231220
948 |d201606016|cEBSCO|tebscoebooksacademic|lridw
994 92|bRID
