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BestsellerE-book

Title RNA interference technology : from basic science to drug development / edited by Krisharao Appasani ; forewords by Andrew Fire and Marshall Nirenberg.

Publication Info. Cambridge, UK ; New York : Cambridge University Press, 2005.

Item Status

Description 1 online resource (xxxiii, 510 pages, 16 unnumbered pages of plates) : illustrations (some color)
Physical Medium polychrome
Description text file
Bibliography Includes bibliographical references and index.
Contents Cover; Half-title; Title; Copyright; Dedication; Contents; Foreword; Foreword; Contributors; Introduction; SECTION ONE Basic RNAi, siRNA, microRNAs and gene-silencing mechanisms; SECTION TWO Design, synthesis of siRNAs; SECTION THREE Vector development and in vivo, in vitro and in ovo delivery methods; SECTION FOUR Gene silencing in model organisms; SECTION FIVE Drug target validation; SECTION SIX Therapeutic and drug development; SECTION SEVEN High-throughput genome-wide RNAi analysis; Index.
Summary RNA Interference (RNAi) technology has rapidly become one of the key methods used in functional genomics. In this cutting-edge overview, the basic concepts of RNAi biology are discussed, as well as the current and potential applications, providing an invaluable reference for all those who need to understand this emerging technology.
Local Note eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America
Subject Small interfering RNA.
Small interfering RNA.
Gene silencing.
Gene silencing.
Genre/Form Electronic books.
Electronic books.
Added Author Appasani, Krishnarao, 1959-
Other Form: Print version: RNA interference technology. Cambridge, UK ; New York : Cambridge University Press, 2005 0521836778 (DLC) 2004054562 (OCoLC)55962410
ISBN 0511082215 (electronic book)
9780511082214 (electronic book)
0511546408 (electronic book)
9780511546402 (electronic book)
9780511081767 (electronic book)
0511081766 (electronic book)
1280163178
9781280163173
Report No. 9780511082214