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BestsellerE-book
Author Holmes, Frederic Lawrence.

Title Meselson, Stahl, and the replication of DNA : a history of "the most beautiful experiment in biology" / Frederic Lawrence Holmes.

Publication Info. New Haven, CT : Yale University Press, 2001.

Item Status

Description 1 online resource (xii, 503 pages) : illustrations
Physical Medium polychrome
Description text file
Bibliography Includes bibliographical references (pages 449-496) and index.
Summary In 1957 Matthew Meselson and Frank Stahl produced a landmark experiment confirming that DNA replicates as predicted by the double helix structure Watson and Crick had recently proposed. It also gained immediate renown as a 'most beautiful' experiment whose beauty was tied to its simplicity. This book vividly reconstructs the complex route that led to the Meselson-Stahl experiment and provides an inside view of day-to-day scientific research - its unpredictability, excitement, intellectual challenge, and serendipitous windfalls, as well as its frustrations, unexpected diversions away from original plans, and chronic uncertainty.
Contents ""Contents""; ""Preface""; ""Acknowledgments""; ""Introduction""; ""The Replication Problem""; ""Meselson and Stahl""; ""Twists and Turns""; ""Crossing Fields: Chemical Bonds to Biological Mutants""; ""Dense Solutions""; ""The Big Machine""; ""Working at High Speed""; ""The Unseen Band""; ""One Discovery, Three Stories""; ""An Extremely Beautiful Experiment""; ""Centrifugal Forces""; ""The Subunits of Semiconservative Replication""; ""Images of an Experiment""; ""Afterword""; ""Abbreviations Used in Notes""; ""Notes""; ""Index""
Local Note eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America
Subject Meselson, Matthew.
Meselson, Matthew.
Stahl, Franklin W.
Stahl, Franklin W.
Meselson, Matthew.
Stahl, Franklin W.
DNA replication -- Experiments -- History.
DNA replication.
History.
Molecular biology -- Experiments -- History.
Molecular biology -- Experiments.
Molecular biology.
DNA Replication.
Molecular Biology -- history.
Genre/Form Electronic books.
Other Form: Print version: Holmes, Frederic Lawrence. Meselson, Stahl, and the replication of DNA. New Haven, CT : Yale University Press, 2001 (DLC) 2001017701
ISBN 9780300129663 (electronic book)
0300129661 (electronic book)
1281730459
9781281730459
9780300085402
0300085400