Description |
1 online resource (xii, 503 pages) : illustrations |
Physical Medium |
polychrome |
Description |
text file |
Bibliography |
Includes bibliographical references (pages 449-496) and index. |
Summary |
In 1957 Matthew Meselson and Frank Stahl produced a landmark experiment confirming that DNA replicates as predicted by the double helix structure Watson and Crick had recently proposed. It also gained immediate renown as a 'most beautiful' experiment whose beauty was tied to its simplicity. This book vividly reconstructs the complex route that led to the Meselson-Stahl experiment and provides an inside view of day-to-day scientific research - its unpredictability, excitement, intellectual challenge, and serendipitous windfalls, as well as its frustrations, unexpected diversions away from original plans, and chronic uncertainty. |
Contents |
""Contents""; ""Preface""; ""Acknowledgments""; ""Introduction""; ""The Replication Problem""; ""Meselson and Stahl""; ""Twists and Turns""; ""Crossing Fields: Chemical Bonds to Biological Mutants""; ""Dense Solutions""; ""The Big Machine""; ""Working at High Speed""; ""The Unseen Band""; ""One Discovery, Three Stories""; ""An Extremely Beautiful Experiment""; ""Centrifugal Forces""; ""The Subunits of Semiconservative Replication""; ""Images of an Experiment""; ""Afterword""; ""Abbreviations Used in Notes""; ""Notes""; ""Index"" |
Local Note |
eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America |
Subject |
Meselson, Matthew.
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Meselson, Matthew. |
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Stahl, Franklin W.
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Stahl, Franklin W. |
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Meselson, Matthew. |
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Stahl, Franklin W. |
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DNA replication -- Experiments -- History.
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DNA replication. |
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History. |
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Molecular biology -- Experiments -- History.
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Molecular biology -- Experiments. |
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Molecular biology. |
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DNA Replication. |
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Molecular Biology -- history. |
Genre/Form |
Electronic books.
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Other Form: |
Print version: Holmes, Frederic Lawrence. Meselson, Stahl, and the replication of DNA. New Haven, CT : Yale University Press, 2001 (DLC) 2001017701 |
ISBN |
9780300129663 (electronic book) |
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0300129661 (electronic book) |
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1281730459 |
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9781281730459 |
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9780300085402 |
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0300085400 |
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