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Title Adipogenesis : signaling pathways, molecular regulation and impact on human disease / Yunfeng Lin and Xiaoxiao Cai, editors.

Publication Info. New York : Nova Biomedical, [2013]

Item Status

Description 1 online resource : illustrations.
text file
Series Cell biology research progress
Cell Biology Research Progress
Cell biology research progress.
Bibliography Includes bibliographical references and index.
Contents ""ADIPOGENESIS ""; ""ADIPOGENESIS ""; ""Library of Congress Cataloging-in-Publication Data ""; ""Contents ""; ""Preface ""; ""Chapter I Molecular Determination of Adipogenic versus Osteogenic Differentiation in Mesenchymal Stem Cells ""; ""Abstract ""; ""Introduction ""; ""Clinical Applications of Mesenchymal Cells ""; ""Transcription Factors""; ""Wnt Signaling ""; ""Hedgehog Signaling""; ""Bone Morphogenetic Protein (BMP) Signaling ""; ""Conclusion ""; ""References ""; ""Chapter II LMNA-Linked Lipodystrophies: Experimental Models to Unravel the Molecular Mechanisms ""; ""Abstract ""
""Lipodystrophies """"The LMNA Gene and the Nuclear Lamina ""; ""Clinical Features and Main Characteristics of Lamina Related Lypodystrophies ""; ""Familial Partial Lipodystrophy, Dunningan Type (FPLD2) ""; ""Mandibuloacral Dysplasia Type A (MADA) ""; ""Mandibuloacral Dysplasia Type B (MADB) ""; ""Hutchinson�Gilford Progeria Syndrome (HGPS) ""; ""HIV-Related Lipodystrophy""; ""LMNA Murine Models ""; ""Development and Testing of Potential Therapeutic Strategies: The Prenylation Dilemma ""; ""Challenging Mouse to Model Human Lipodystrophy ""
""Adipocyte Differentiation from Mesenchymal Stem Cells """"Human Adipogenesis Cell Models Based on Stem Cells ""; ""A Model of Lipodystrophy Based on Prelamin a Accumulating hMSCs ""; ""Adipogenesis Models Based on Induced Pluripotent Stem Cells (iPSCs) ""; ""Conclusion ""; ""References ""; ""Chapter III Adipogenesis and Osteoblastgenesis toward the Ageing Intervention in the 21st Century ""; ""Abstract ""; ""Abbreviations ""; ""1. Ageing in the World ""; ""2. Teeth and Cognitive Functions in Elderly People""; ""3. Fat and Bone in Elderly People ""
""4. Adipogenesis and Osteoblastgenesis from Mesenchymal Stem Cells""""5. Chemical-Regulated Adipogenesisand Osteoblastgenesis ""; ""6. PPAR in Adipocyte and Runx2 in Osteoblast ""; ""7. Drug (TZD) Regulated Adipogenesis and Osteoblastgenesis ""; ""8. Estrogen Effect on Both Adipogenesis and Osteoblastgenesis ""; ""9. Prostaglandin J2 (PGJ2) Regulate Both Adipogenesis and Osteoblastgenesis ""; ""10. Prostaglandin X2 (PGX2) Regulate Both Adipogenesis and Osteoblastgenesis ""; ""11. Nanotechnology for Identification of Chemical Target Protein""; ""11.1. Arginine ""
""11.2. Prostaglandin J (PGJ2) 2 """"Conclusion ""; ""References ""; ""Chapter IV Role of Wnt/ -Catenin Signaling in Bone Marrow adiposity Following Cancer Chemotherapy ""; ""Abstract ""; ""I. Introduction ""; ""II. Osteogenesis, Adipogenesis, and Regulation by Wnt/ -Catenin Signaling Pathway ""; ""Osteogenesis and Osteogenic Transcription Factors ""; ""Adipogenesis and Adipogenic Transcription Factors and Regulators ""; ""Wnt Signaling Pathway in Osteogenic and Adipogenic Commitment and Differentiation ""
Summary Adipogenesis is the process of cell differentiation by which preadipocytes become adipocytes. Adipogenesis has been one of the most intensively studied models of cellular differentiation. The exact mechanisms of adipogenesis remain unclear, since it involves abundant gene, growth factors, cytokines and environmental factors. This book provides an in-depth overview of current knowledge about the subject of adipogenesis in the human body, including what is known about molecular mechanisms (e.g. cytokine- and growth-factor-related). Transcriptional regulators control the expression of target gene.
Local Note eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America
Language English.
Subject Adipose tissues.
Adipose tissues.
Cell differentiation.
Cell differentiation.
Genre/Form Electronic books.
Electronic books.
Added Author Lin, Yunfeng, editor.
Cai, Xiaoxiao, editor.
Other Form: Print version: Adipogenesis New York : Nova Biomedical, [2013] 9781628087505 (DLC) 2013945715
ISBN 9781628087536 (ebook)
1628087536
9781628087505
1628087501 (hardback)