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Title Extracellular matrix: pathobiology and signaling / edited by Nikos K. Karamanos.

Publication Info. Berlin : Walter de Gruyter, [2012]
©2012

Item Status

Description 1 online resource (l, 888 pages :) : illustrations, portraits
Physical Medium polychrome
Description text file
Bibliography Includes bibliographical references and index.
Contents An introduction to the extracellular matrix molecules and their importance in pathobiology and signaling / Achilleas Theocharis ... [et al.] -- Insights into the function of glycans / Paraskevi Heldin -- Proteoglycans : structure, pathobiology, and signaling / Liliana Schaefer -- ECM cell surface receptors / Donald Gullberg -- Extracellular proteinases / Jan-Olof Winberg -- Collagen : not just mechanics, for the high degree of connectivity grounded on the apparently simple triple helix / Ruggero Tenni -- Emerging aspects in extracellular matrix pathobiology / Achilleas Theocharis -- Targeting tumor microenvironment at the ECM level / Nikos K. Karamanos.
Summary Over the last decades cell biology and biological chemistry have increasingly turned their attention to the space between cells and revealed an elaborate network of macromolecules essential for structural support, cell migration, adhesion and signaling. This comprehensive handbook of the extracellular matrix is organized into seven thematic sections, giving an overview of the current state of knowledge of matrix components (structure and function), their roles in health and disease (matrix pathobiology) as well as new concepts of pharmacological targeting.
Local Note eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America
Subject Extracellular matrix.
Extracellular matrix.
Cellular signal transduction.
Cellular signal transduction.
Genre/Form Electronic books.
Added Author Karamanos, Nikos K.
ProQuest (Firm)
Other Form: Print version: 9783110258769 3110258765 (DLC) 2012019181
ISBN 9783110258769 alkaline paper
9783110258776 e-book
3110258773
9783110258776
3110258765
Standard No. 9786613940193