| Edition |
First edition. |
| Description |
1 online resource (112 pages) : illustrations |
|
text file |
| Contents |
1. Pharmacokinetics and Terminology -- 1.1 Oral Bioavailability (Fos) -- 1.2 Apparent Volume of Distribution (Vd) -- 1.3 Plasma Clearance (CL) -- 1.4 Area Under the Plasma Concentration-time Curve (AUC) -- 1.5 Plasma Elimination Half-life (t1/2) -- 1.6 Steady State Plasma Concentration (Css) -- 1.7 Loading Dose (LD) -- 1.8 Maintenance Dose (MD) -- 2. Pharmacokinetics and Polytherapy -- 2.1 Cytochrome P450 (CYP) -- 2.2 P170 Glycoprotein (Pgp) -- 3. Pharmacokinetics and Dosing Regimen -- 4. Pharmacokinetics and Patient Pathophysiology -- 4.1 Age -- 4.2Renal Failure -- 4.3 Hepatic Failure -- 4.4 The Critically Ill Patient -- 5. Pharmacokinetics and Pharmaceutical Technology -- 5.1 Liposomal Formulations -- 5.2 Controlled Release or Depot Formulations -- 5.3 Prodrugs -- 6. Pharmacokinetics and Pharmacogenetics -- 6.1 Polymorphism of Phase I Enzymes -- 6.2 Polymorphism of Phase II Enzymes -- 7. Pharmacokinetics and Pharmacodynamics -- 7.1 Pharmacokinetic-pharmacodynamic (PK/PD) Relationships in Antibiotic Therapy -- 7.2 Pharmacokinetic-pharmacodynamic (PK/PD) Relationships in Antifungal Therapy -- 8. Conclusions -- References -- Glossary -- Author. |
| Summary |
This book provides a practical introduction to the main concepts of pharmacokinetics and how they can be applied in clinical settings, without using complicated mathematical equations. Essential information on approaches to drug-dosing and monitoring in special populations, including patients with renal and hepatic diseases and elderly patients, are given. Charts, illustrations and examples of calculations are added to clarify concepts and terminology of pharmacokinetics. It's a guide for students and clinicians who want clear, useful guidance to the basic principles of pharmacokinetics and th. |
| Bibliography |
Includes bibliographical references. |
| Local Note |
eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America |
| Subject |
Pharmacokinetics.
|
|
Pharmacokinetics. |
|
Pharmacology.
|
|
Pharmacology. |
| Genre/Form |
Electronic books.
|
| Other Form: |
Print version: Pea, Federico. Pharmacokinetics in Everyday Clinical Practice. Torino : SEEd, ©2012 9788897419174 |
| ISBN |
9788897419181 (electronic book) |
|
8897419186 (electronic book) |
|
9788897419174 |
|
8897419178 |
|
