| Description |
1 online resource (viii, 255 pages) |
| Physical Medium |
polychrome |
| Description |
text file |
| Contents |
RESEARCH PROGRESS IN ALZHEIMER'S DISEASE AND DEMENTIA VOLUME 6; RESEARCH PROGRESS IN ALZHEIMER'S DISEASE AND DEMENTIA VOLUME 6; Library of Congress Cataloging-in-Publication Data; CONTENTS; PREFACE; Chapter 1: "LOSS OF THE FUTURE": PROSPECTION IMPAIRMENTS IN THE DEMENTIAS; ABSTRACT; ABBREVIATIONS; 1. INTRODUCTION; 1.1. The Many Functions of Memory Retrieval; 1.2. Episodic Memory as a Constructive Endeavor; 1.3. What Is Prospection?; 1.4. Assessment of Prospection; 2. CHANGES IN PROSPECTION IN HEALTHY AGING; 3. EVIDENCE FOR PERVASIVE FUTURE THINKING DEFICITS IN DEMENTIA |
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3.1. Alzheimer's Disease3.1.1. Similarities across Past and Future Contexts in AD; 3.1.2. Neural Correlates of Prospection Deficits in AD; 3.1.3. Scene Construction in AD; 3.2. Amnestic Mild Cognitive Impairment; 3.2.1. Future Directions for Prospection Research In AD and aMCI; 3.3. Semantic Dementia; 3.3.1. Functional Neuroimaging of Future Simulation in SD; 3.3.2. Vulnerability of Contextual Details during Future Simulation in SD; 3.3.3. Reconfiguring of Details during Prospection; 3.4. Behavioral-Variant Frontotemporal Dementia; 3.5. Parkinson's Disease |
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3.6. Relationship between Prospection and Functional Impairment in Dementia3.6.1. Prospective Memory in Neurodegenerative Disorders; 3.6.2. Decision-Making Capacity and Prospection in Dementia; 3.6.3. How Loss of the Future Impacts the Self in Dementia; CONCLUSION; ACKNOWLEDGMENTS; REFERENCES; Chapter 2: MEMORY BINDING IN ALZHEIMER'S DISEASE; ABSTRACT; ABBREVIATIONS; 1. INTRODUCTION; 2. THE BINDING PROBLEM; 3. TYPES OF BINDING; 4. MEMORY BINDING IN HEALTHY AGING AND AD; 4.1. Memory Binding in Healthy Aging; 4.2. Memory Binding in AD; 5. MEMORY BINDING IN THE EARLY DIAGNOSIS OF AD |
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6. MEMORY BINDING IN THE DIFFERENTIAL DIAGNOSIS OF AD6.1. Studies in Depression; 6.2. Study in Non-AD Dementias; 7. MEMORY BINDING AND THE BRAIN: INSIGHTS INTO THE AD PATHOLOGY; 8. MEMORY BINDING AND PREVENTION INITIATIVES FOR AD; CONCLUSION; ACKNOWLEDGMENTS; REFERENCES; Chapter 3: ALZHEIMER'S DISEASE THERAPY TARGETING BACE1 AND NEPRILYSIN; ABSTRACT; ABBREVIATIONS; 1. INTRODUCTION; 2. APP PROCESSING, Ab PRODUCTION AND Ab DEGRADATION; 3. PRECLINICAL TESTING OF THERAPEUTIC BACE1 INHIBITION; 3.1. Memory Rescue by BACE1 Null Knockout in APP Mice; 3.2. Phenotypes of BACE1 Null Knockout per se |
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3.3. BACE1 Haploinsufficiency3.4. Benefits of BACE1 Haploinsufficiency Lessen in APP Mice with Disease Progression; 3.5. BACE1 Inhibitors; 3.6. Strategies to Block BACE1-Elevating Pathways; 3.7. Other Approaches to Inhibit BACE1 Processing of APP; 4. PRECLINICAL TESTING OF THERAPEUTIC NEPRILYSIN ACTIVATION; 4.1. Transgenic Overexpression of Neprilysin; 4.2. Gene Transfer and Pharmacological Strategies to Elevate Neprilysin Expression; 5. PRECLINICAL TESTING OF COMBINATION Ab-LOWERING THERAPIES; CONCLUSION; ACKNOWLEDGMENTS; REFERENCES; Chapter 4: ADVANCES IN TAU IMMUNOTHERAPY; ABSTRACT |
| Local Note |
eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America |
| Subject |
Alzheimer's disease.
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Alzheimer's disease. |
| Genre/Form |
Electronic books.
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| Added Author |
Sun, Miao-Kun, editor.
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| Other Form: |
Print version: Research progress in Alzheimer's disease and dementia. Volume 6. New York : Nova Biomedical, [2016] 9781634851725 (OCoLC)957521778 |
| ISBN |
9781634852067 (electronic book) |
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1634852060 (electronic book) |
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9781634851725 |
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1634851722 |
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