| Description |
1 online resource (xiii, 567 pages) : illustrations (some color) |
|
text file |
| Bibliography |
Includes bibliographical references. |
| Contents |
Ch. 1. The preoccupations of twenty-first-century biology / David Baltimore -- ch. 2. The world as physics, mathematics and nothing else / Alexander Varshavsky -- ch. 3. Physical biology: 4D visualization of complexity / Ahmed H. Zewail -- ch. 4. Revolutionary developments from atomic to extended structural imaging / John Meurig Thomas -- ch. 5. Physical biology at the crossroads / Carlos J. Bustamante -- ch. 6. The challenge of quasi-regular structures in biology / Roger D. Kornberg -- ch. 7. The future of biological X-ray analysis / Douglas C. Rees -- ch. 8. Reinterpreting the genetic code: implications for macromolecular design, evolution and analysis / David A. Tirrell -- ch. 9. Designing ligands to bind tightly to proteins / George M. Whitesides ... [et al.] -- ch. 10. Biology by the numbers / Rob Phillips -- ch. 11. Eppur si muove / Michele Parrinello -- ch. 12. Protein folding and beyond: energy landscapes and the organization of living matter in time and space / Peter G. Wolynes -- ch. 13. Protein folding and misfolding: from atoms to organisms / Christopher M. Dobson -- ch. 14. A systems approach to medicine will transform healthcare / Leroy Hood -- ch. 15. The neurobiology of consciousness / Christof Koch and Florian Mormann -- ch. 16. Computer-aided drug discovery: physics-based simulations from the molecular to the cellular level / J. Andrew McCammon -- ch. 17. Precision measurements in biology / Stephen R. Quake -- ch. 18. Potassium channels and the atomic basis of selective ion conduction / Roderick MacKinnon -- The 2007 Welch award papers. ch. 19. Symmetry breaking, delocalization and dynamics in electron transfer systems / Noel S. Hush. ch. 20. The initial value representation of semiclassical theory: a practical way for adding quantum effects to classical molecular dynamics simulations of complex molecular systems / William H. Miller -- Biographies. |
| Summary |
This is an avant-garde book edited by Nobel Laureate Ahmed Zewail with contributions from eminent scientists including four Nobel prize winners. The perspectives of these world leaders in physics, chemistry, and biology define potential new frontiers at the interface of disciplines and including physical, systems, and synthetic biology. This book brings about the confluence of concepts and tools, and that of different disciplines, to address significant problems of our time: visualization; theory and computation for complexity; macromolecular function, protein folding and misfolding; and systems integration from cells to consciousness. The scope of tools is wide-ranging, spanning imaging, crystallography, microfluidics, single-molecule spectroscopy, and synthetic probe targeting. Concepts such as dynamic self-assembly, molecular recognition, non-canonical amino acids, and others are covered in various chapters as they are cornerstones in building the trilogy description of behavior-structure, dynamics, and function. The volume is uniquely structured to provide overviews with historical perspectives on the evolution of ideas and on the future of physical biology and biological complexity, from atoms to medicine. |
| Local Note |
eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America |
| Subject |
Biophysics.
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Biophysics. |
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Biochemistry.
|
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Biochemistry. |
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Molecular biology.
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Molecular biology. |
| Genre/Form |
Electronic books.
|
| Added Author |
Zewail, Ahmed H.
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| Other Form: |
Print version: Physical biology. London, UK : Imperial College Press, ©2008 (DLC) 2008009371 |
| ISBN |
1848162014 (electronic book) |
|
9781848162013 (electronic book) |
|
1848162006 (Paper) |
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1848161999 (Cloth) |
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