LEADER 00000cam a2200817 i 4500
001 on1266896757
003 OCoLC
005 20220930060851.0
006 m o d
007 cr cn|||||||||
008 210802s2021 dcua ob 000 0 eng
010 2021938584
016 7 9918232002406676|2DNLM
019 1286906953|a1300799155
020 |z9780309303361
020 |z0309303362
020 9780309304085|q(electronic book)
020 0309304083|q(electronic book)
035 (OCoLC)1266896757|z(OCoLC)1286906953|z(OCoLC)1300799155
040 NLM|beng|erda|cNLM|dN$T|dSFB|dOCLCF|dVT2|dYDX|dOCLCO
042 pcc
049 RIDW
050 4 QP376
082 04 612.82|223
090 QP376
110 2 National Academies of Sciences, Engineering, and Medicine
(U.S.).|bCommittee on Ethical, Legal, and Regulatory
Issues Associated with Neural Chimeras and Organoids,
|0https://id.loc.gov/authorities/names/n2022180607
|eauthor.
245 14 The emerging field of human neural organoids, transplants,
and chimeras :|bscience, ethics, and governance /
|cCommittee on Ethical, Legal, and Regulatory Issues
Associated with Neural Chimeras and Organoids; Committee
on Science, Technology, and Law; Policy and Global
Affairs; National Academies of Sciences, Engineering,
Medicine.
264 1 Washington, DC :|bNational Academies Press,|c[2021]
300 1 online resource (1 PDF file (xvi, 136 pages)) :
|billustrations.
336 text|btxt|2rdacontent
337 computer|bc|2rdamedia
338 online resource|bcr|2rdacarrier
340 |gpolychrome|2rdacc
347 text file|2rdaft
490 1 Consensus study report of the National Academies of
Sciences, Engineering, Medicine
504 Includes bibliographical references.
505 0 Front Matter -- Summary -- 1. Introduction -- 2. The
Science of Human Neural Organoids, Transplants, and
Chimeras -- 3. Ethical Concerns -- 4. Oversight and
Governance -- 5. Public Engagement -- 6. Findings of the
Committee -- References -- Appendix A: Biographies of
Committee and Staff Members -- Appendix B: Committee
Meeting Agendas.
520 3 Each year, tens of millions of individuals in the U.S.
suffer from neurological and psychiatric disorders
including neurodegenerative diseases such as Alzheimer's
Disease and Parkinson's Disease, and psychiatric disorders
such as autism spectrum disorder, depression and
schizophrenia. Treatments for these diseases are often
completely lacking or only partially effective, due in
large part to the difficulty of conducting brain research
and the complexity of the brain itself. Researchers in
recent years have developed new models to better represent
and study the human brain. The three models considered in
this report, all of which generate and use pluripotent
stem cells from healthy individuals and patients, are
human neural organoids, human neural transplants, and
human-animal neural chimeras. The Emerging Field of Human
Neural Organoids, Transplants, and Chimeras: Science,
Ethics, and Governance reviews the status of research,
considers its benefits and risks, discusses associated
ethical issues, and considers governance mechanisms for
this type of research.
536 This activity was supported by contracts from the National
Institutes of Health (Sponsor Award Number
HHSN263201800029I/75N98019F00861) and The Dana Foundation.
This Project has been funded in whole or in part with
federal funds from the National Institutes of Health,
Department of Health and Human Services, under Contract
No. HHSN263201800029I. Any opinions, findings, conclusions,
or recommendations expressed in this publication do not
necessarily reflect the views of any organization or
agency that provided support for the project.
588 Description based on online resource; title from PDF title
page (viewed February 17, 2022).
590 eBooks on EBSCOhost|bEBSCO eBook Subscription Academic
Collection - North America
650 0 Neurophysiology.|0https://id.loc.gov/authorities/subjects/
sh85091159
650 0 Tissues.|0https://id.loc.gov/authorities/subjects/
sh85135594
650 0 Transplantation of organs, tissues, etc.|0https://
id.loc.gov/authorities/subjects/sh85137008
650 0 Chimerism.|0https://id.loc.gov/authorities/subjects/
sh2011001809
650 0 Medical ethics.|0https://id.loc.gov/authorities/subjects/
sh85082929
650 0 Medical genetics.|0https://id.loc.gov/authorities/subjects
/sh85082937
650 0 Brain|xDiseases|0https://id.loc.gov/authorities/subjects/
sh85016332|xAlternative treatment.|0https://id.loc.gov/
authorities/subjects/sh99002316
650 0 Cell organelles.|0https://id.loc.gov/authorities/subjects/
sh85021661
650 0 Intracerebral transplantation.|0https://id.loc.gov/
authorities/subjects/sh92005956
650 7 Neurophysiology.|2fast|0https://id.worldcat.org/fast/
1036464
650 7 Tissues.|2fast|0https://id.worldcat.org/fast/1151499
650 7 Transplantation of organs, tissues, etc.|2fast|0https://
id.worldcat.org/fast/1154919
650 7 Chimerism.|2fast|0https://id.worldcat.org/fast/1765046
650 7 Medical ethics.|2fast|0https://id.worldcat.org/fast/
1014081
650 7 Medical genetics.|2fast|0https://id.worldcat.org/fast/
1014133
650 7 Brain|xDiseases.|2fast|0https://id.worldcat.org/fast/
837607
650 7 Cell organelles.|2fast|0https://id.worldcat.org/fast/
850212
650 7 Intracerebral transplantation.|2fast|0https://
id.worldcat.org/fast/977743
651 2 United States.|0https://id.nlm.nih.gov/mesh/D014481
655 4 Electronic books.
710 2 National Academies of Sciences, Engineering, and Medicine
(U.S.).|bCommittee on Science, Technology, and Law,|0https
://id.loc.gov/authorities/names/n2016187669|eissuing body.
776 08 |iPrint version:|z9780309303361|z0309303362
|w(OCoLC)1245923126
830 0 Consensus study report.|0https://id.loc.gov/authorities/
names/n2017188206
856 40 |uhttps://rider.idm.oclc.org/login?url=https://
search.ebscohost.com/login.aspx?direct=true&scope=site&
db=nlebk&AN=3024816|zOnline ebook via EBSCO. Access
restricted to current Rider University students, faculty,
and staff.
856 42 |3Instructions for reading/downloading the EBSCO version
of this ebook|uhttp://guides.rider.edu/ebooks/ebsco
901 MARCIVE 20231220
948 |d20221222|cEBSCO|tEBSCOebooksacademic NEW 9-30quarterly
3071|lridw
994 92|bRID
