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Title Brain banking / edited by Ingeborg Huitinga and Maree J. Webster.

Publication Info. Amsterdam : Elsevier, [2018]
©2018

Item Status

Description 1 online resource (xvi, 430 pages) : illustrations (chiefly color)
Series Handbook of clinical neurology ; volume 150
Handbook of clinical neurology ; v. 150.
Bibliography Includes bibliographical references and index.
Contents Section I. Brain donor recruitment strategies. The Netherlands Brain Bank for Psychiatry -- Brain donation procedures in the sudden death brain bank in Edinburgh -- Section II. Brain bank networks. Autism BrainNet -- The NIH NeuroBioBank: Creating opportunities for human brain research -- Section III. Ethical Aspects of Brain Banking and Management of Brain Banks -- Design of a European code of conduct for brain banking -- A review of brain biorepository management and operations -- A new viewpoint: running a non-profit brain bank as a business -- Section IV. Brain dissection, tissue processing and tissue dissemination. The New York Brain Bank of Columbia University: Practical highlights of 35 years of experience -- Neurochemical markers as potential indicators of post-mortem tissue quality -- Section V. Neuropathological diagnosis. Minimal neuropathological diagnosis for brain banking in the normal middle aged and aged brain and in neurodegenerative disorders -- Brain donation at autopsy: Clinical characterization and toxicological analyses -- Section VI. Brain donor data: clinical, genetic, radiologic and research data storage and mining. Information technology for brain banking -- Collecting, storing and mining research data in a brain bank -- What can we learn about brain donors? Use of clinical information in human postmortem brain research -- The art of matching brain tissue from patients and controls for postmortem research -- Section VII. Human brain tissue analyses: old and new techniques. Considerations for optimal use of postmortem human brains for molecular psychiatry: Lessons from schizophrenia -- Epigenetic analysis of human brain tissue -- Laser microdissection and gene expression profiling in the human postmortem brain -- Purification of cells from fresh human brain tissue: Primary human glial cells -- Proteomics and lipidomics in the human brain -- 3-D imaging in the post-mortem human brain with CLARITY and CUBIC -- Neuronal life after death: Electrophysiological recordings from neurons in adult human brain tissue obtained through surgical resection or post-mortem -- Post-mortem magnetic resonance imaging -- Cyto- and receptorarchitectonic mapping of the human brain -- Mapping pathological circuitry in schizophrenia
Summary "Brain Banking, Volume 150, serves as the only book on the market offering comprehensive coverage of the functional realities of brain banking. It focuses on brain donor recruitment strategies, brain bank networks, ethical issues, brain dissection/tissue processing/tissue dissemination, neuropathological diagnosis, brain donor data, and techniques in brain tissue analysis. In accordance with massive initiatives, such as BRAIN and the EU Human Brain Project, abnormalities and potential therapeutic targets of neurological and psychiatric disorders need to be validated in human brain tissue, thus requiring substantial numbers of well characterized human brains of high tissue quality with neurological and psychiatric diseases"--Publisher's description
Local Note eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America
Subject Brain banks.
Preservation of organs, tissues, etc.
Tissue banks.
Organ donors.
HEALTH & FITNESS -- Diseases -- General.
MEDICAL -- Clinical Medicine.
MEDICAL -- Diseases.
MEDICAL -- Evidence-Based Medicine.
MEDICAL -- Internal Medicine.
Brain banks
Preservation of organs, tissues, etc.
Genre/Form Internet Resources.
Added Author Huitinga, Ingeborg, editor.
Webster, Maree J., editor.
Other Form: Print version: Brain banking. Amsterdam : Elsevier, [2018] 9780444636393 (OCoLC)991683664
ISBN 9780444636423 (electronic bk.)
0444636420 (electronic bk.)
9780444636393 (hardcover)
0444636390 (hardcover)