| Description |
1 online resource : illustrations. |
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text file |
| Series |
Biochemistry Research Trends Ser.
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Biochemistry research trends series.
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| Contents |
Intro -- Contents -- Preface -- Chapter 1 -- Novel Cyanine Dyes as Inhibitors of Insulin Fibrillization -- Abstract -- Introduction -- Materials and Methods -- Experimental -- Insulin Aggregation Assessed by Thioflavin T Assay -- Transmission Electron Microscopy -- Fluorescence Microscopy -- Quantum-Chemical Calculations -- Docking Studies -- Molecular Dynamics Simulations -- Results and Discussion -- Kinetics of Insulin Fibrillization in the Presence of Cyanine Dyes |
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Transmission and Fluorescence Microscopy Studies of the Insulin Aggregates Obtained in the Presence of the Cyanine Compounds -- Correlation of the Inhibitory Potency with the Quantum-Chemical Characteristics of the Cyanine Dyes -- Insulin Binding Sites for the Most Effective Cyanine Inhibitors Revealed by Molecular Docking -- Molecular Dynamics Simulations of Insulin Interactions with the Most Effective Cyanine Inhibitors of the Protein Fibrillization -- Conclusion -- References -- Chapter 2 -- Interactions between the Novel Cyanine Dyes and Biological Macromolecules -- Abstract |
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Introduction -- Materials and Methods -- Experimental -- Preparation of Working Solutions -- Spectroscopic Measurements -- Binding Model -- Docking Studies -- Results and Discussion -- Spectroscopic Characterization of Cyanine Dyes in Methanol and in Buffer Solution -- The Association of Cyanine Dyes with the DNA -- Interactions between Monomethine Cyanine Dyes and the Double Stranded DNA -- Modulating Effect of the DNA on Aggregation Behaviour of Heptamethine and Pentamethine Dyes -- Binding of Cyanine Dyes to the Lipid Vesicles |
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Binding of Heptamethine Cyanine Dyes to the Model Lipid Membranes -- Binding of Pentamethine Cyanine Dyes to the Model Lipid Membranes -- Association of Cyanine Dyes with Bovine Serum Albumin -- Interaction of Cyanine Dyes with Native and Fibrillar Lysozyme -- Heptamethine Cyanine Dye response to the Native Lysozyme -- Modulation Effect of the Fibrillar Lysozyme on Aggregation Behaviour of Heptamethine Dyes -- Conclusion -- References -- Chapter 3 -- Cyanine Dyes, J- and H- Aggregation in the Presence of Nanoparticles: Experimental and Theoretical Approach and Application -- Abstract |
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1. Introduction -- 2. Self-Organization of Cyanine Dyes -- 2.1. H- and J-Aggregation of Cyanine Dyes -- 2.2. Optical Properties of Cyanine Dyes -- 3. J- Aggregation of Thiacyanine Dyes on NPs -- 3.1. Noble Metal Nanoparticles -- 3.2. NPs Characterization -- 3.2.1. Nanospectroscopy Techniques -- 3.2.2. Nanomicroscopy Techniques -- 3.3. Modification of AgNPs and AuNPs Surface with Thiacyanine Dyes -- 3.4. Nanospectroscopy and Nanomicroscopy Methods for Dye-NPs Assembly Characterization -- 3.4.1. UV Vis Spectrophotometry and Fluorescence Spectroscopy |
| Local Note |
eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America |
| Subject |
Cyanines.
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Cyanines. |
| Genre/Form |
Electronic books.
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| Added Author |
Zimmerman, Douglas, editor.
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| Other Form: |
Print version: Cyanine dyes. New York : Nova Science Publishers, [2019] (DLC) 2019949044 |
| ISBN |
153616240X |
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9781536162400 (electronic book) |
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9781536162394 (hardcover) |
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