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Author Bins, Adriaan Dirk.

Title Induction and analysis of antigen-specific T cell responses in melanoma patients and animal models / Adriaan Dirk Bins.

Publication Info. [Leiden] : Leiden University Press, [2007]
©2007

Item Status

Edition 2nd ed.
Description 1 online resource (148 pages) : illustrations (some color)
Physical Medium polychrome
Description text file
Thesis Proefschrift--Universiteit Leiden, 2007.
Bibliography Includes bibliographical references.
Contents Introduction; Ch. 1: On the Role of Melanoma-Specific CD8+ T-Cell Immunity in Disease Progression of Advanced-Stage Melanoma Patients.; Ch. 2:Phase I clinical study with multiple peptide vaccines in combination with tetanus toxoid and GM-CSF in advanced-stage HLA-A*0201- positive melanoma patients.; Ch. 3: A rapid and potent DNA vaccination strategy defined by in vivo monitoring of antigen expression; Ch. 4:Superior immunogenicity of DNA tattooing as compared to intramuscular DNA vaccination in non-human primates.; Ch. 5: In vivo antigen stability affects vaccine efficacy.
Summary In the last century, it has become clear that in patients suffering certain types of cancer, spontaneous activation of the immune sytem may lead to curation. The concept of immunotherapy is based on that notion. The intention is to stimulate T cells direc.
Local Note eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America
Language Summary in Dutch.
Subject Melanoma -- Immunological aspects -- Research.
Melanoma -- Immunological aspects.
Research.
Melanoma.
Immunocompetent cells -- Research.
Immunocompetent cells.
T cells -- Research.
T cells -- Research.
T cells.
Cancer vaccines -- Research.
Cancer vaccines.
Genre/Form Electronic books.
Academic theses.
Academic theses.
Other Form: Print version: Bins, Adriaan Dirk. Induction and analysis of antigen-specific T cell responses in melanoma patients and animal models. 2nd ed. [Leiden] : Leiden University Press, ©2007 9789087280116 9087280114 (OCoLC)150460062
ISBN 9789048505913 (electronic book)
9048505917 (electronic book)