LEADER 00000cam a22006018i 4500 001 ocn957554849 003 OCoLC 005 20180130100540.5 006 m o d 007 cr ||||||||||| 008 160829s2016 nyu ob 001 0 eng 010 2016039857 020 9781536101539|q(electronic book) 020 1536101532|q(electronic book) 020 |z9781536101362|q(hardcover) 035 (OCoLC)957554849 040 DLC|beng|erda|cDLC|dOCLCO|dN$T|dEBLCP 042 pcc 049 RIDW 050 10 QP552.C3 072 7 SCI|x007000|2bisacsh 082 00 572/.69|223 090 QP552.C3 245 00 Carnosine :|bphysiological effects and research insights / |ceditor, Dominic Wells. 263 1612 264 1 Hauppauge, New York :|bNova Science Publisher's, Inc., |c[2016] 300 1 online resource. 336 text|btxt|2rdacontent 337 computer|bn|2rdamedia 338 online resource|bnc|2rdacarrier 347 text file|2rdaft 490 1 Biochemistry research trends 504 Includes bibliographical references and index. 505 0 Preface; Carnosine: Benefits in Meat and; Meat Products Quality and Consumer Health; Abstract; Introduction; Oxidation in Meat and Meat Products; Lipid Oxidation; Protein Oxidation; Factors Influencing Lipid and Protein Oxidation; Antioxidant Strategies against Oxidation of Meat and Meat Products; Mechanisms Mediating the Antioxidant Capacity of Carnosine; Carnosine Content in Meat and Meat Products; Conclusion; References; Biographical Sketches; Perspective Role of Carnosine in Tumor-Related Phenomena; Abstract; 1. Introduction; 1.1. Tumor Microenvironment; 1.1.1. Tumor Hypoxia 505 8 1.1.2. Hypoxia Induced Carbonic Anhydrase IX1.2. Basic Features of Carnosine; 2. Influence of Carnosine on Tumor Related Acidosis and Its Consequences; 2.1. Suppression of Extracellular Acidosis and Transport Metabolon Formation; 2.2. Effect of Carnosine on Tumor Cells Migration and Invasion; 2.2.1. Interactions between Carnosine and Matrix Metalloproteases; 3. The Impact of Carnosine on Tumor Cell Metabolism; 3.1. Modulation of Cell Hypoxic Response by Carnosine; 3.2. Antioxidative Effect of Carnosine; 3.3. Glycolysis Pathway as a Target of Carnosine Action 505 8 3.3.1. Glycolytic Enzymes Regulated by Hypoxia3.3.2. Possible Mechanisms of Carnosine Control of Glycolysis; 3.4. Carnosine and Mitochondrial Respiration; 4. Different Ways of the Carnosine Influence on Tumor Cell Proliferation; 4.1. Carnosine and Cell Cycle Regulation; 4.2. Carnosine as a Mimic of Rapamycin in mTOR Signaling Pathway; 5. Possible Use of Carnosine during Anticancer Therapy; 5.1. Platinum Based Drugs and Carnosine; 5.2. Intercalating Chemotherapeutics and Carnosine; 5.3. Protective Effects of Carnosine during Chemotherapy and Radiotherapy; Conclusion; Acknowledgments 505 8 Carnosine: A Regulator of Metal Homeostasis in the SynapseConclusion; References; Neurotropic and Protective Effects of L-carnosine: Studies In Vitro; Abstract; Introduction; Material and Methods; Results; Neurotropic Effects of L-Carnosine; Effects L-Carnosine on Plasticity in Olfactory Cortex Slices; The Protective Effect of L- Carnosine in the Model of Hemorrhagic Stroke in Vitro; The Protective Effect of L-Carnosine on the Activity of Ionotropic Glutamatergic Receptor Mechanisms after Freezing/Rewarming of Brain Slices 588 Description based on print version record and CIP data provided by publisher; resource not viewed. 590 eBooks on EBSCOhost|bEBSCO eBook Subscription Academic Collection - North America 650 0 Carnosine|0https://id.loc.gov/authorities/subjects/ sh85020385|xHealth aspects.|0https://id.loc.gov/ authorities/subjects/sh00005598 650 0 Carnosine|0https://id.loc.gov/authorities/subjects/ sh85020385|xPhysiological effects. 650 7 Carnosine.|2fast|0https://id.worldcat.org/fast/847694 655 4 Electronic books. 700 1 Wells, Dominic,|0https://id.loc.gov/authorities/names/ nb2011004930|eeditor. 776 08 |iPrint version:|tCarnosine|dHauppauge, New York : Nova Science Publisher's, Inc., [2016]|z9781536101362|w(DLC) 2016039598 830 0 Biochemistry research trends series.|0https://id.loc.gov/ authorities/names/n2009180480 856 40 |uhttps://rider.idm.oclc.org/login?url=http:// search.ebscohost.com/login.aspx?direct=true&scope=site& db=nlebk&AN=1406232|zOnline eBook. Access restricted to current Rider University students, faculty, and staff. 856 42 |3Instructions for reading/downloading the EBSCO version of this eBook|uhttp://guides.rider.edu/ebooks/ebsco 901 MARCIVE 20231220 948 |d20180209|cEBSCO|tEBSCOebooksacademic NEW 1-29-18|lridw 994 92|bRID