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Title Principles of cellular engineering : understanding the biomolecular interface / edited by Michael R. King.

Publication Info. Amsterdam ; Boston : Elsevier Academic Press, [2006]
©2006

Item Status

Description 1 online resource (xv, 314 pages, 7 unnumbered pages of plates) : illustrations (some color)
Physical Medium polychrome
Description text file
Bibliography Includes bibliographical references and index.
Contents Traction forces exerted by adherent cells / by Cynthia A. Reinhart-King and Daniel A. Hammer -- Control of endothelial cell adhesion by mechanotransmission from cytoskeleton to substrate / by Rosalind E. Mott and Brian P. Helmke -- Use of hydrodynamic shear stress to analyze cell adhesion / by David Boettiger -- Cellular tensegrity models and cell-substrate interactions / by Dimitrije Stamenović, Ning Wang, and Donald E. Ingber -- Bond formation during cell compression / by Elena Lomakina and Richard E. Waugh -- Dynamics of the neutrophil surface during emigration from blood / Thomas R. Gaborski and James L. McGrath -- Glycocalyx regulation of cell adhesion / Philippe Robert, Laurent Limozin, Anne-Marie Benoliel, Anne Pierres, and Pierre Bongrand -- Atomistic modeling of protein adsorption to ceramic biomaterials in water: a first step toward realistic simulation of the biomaterials surface in vivo / by Alan H. Goldstein -- Model cell membrane surfaces for measuring receptor-ligand interactions / by Craig D. Blanchette, Timothy V. Ratto, and Marjorie L. Longo -- A flow chamber for capillary networks: leukocyte adhesion in capillary sized, ligand-coated micropipettes / by David F.J. Tees, Prithu Sundd, and Douglas J. Goetz -- Adhesion of flowing neutrophils to model vessel surfaces: constraint and regulation by the local hemodynamic environment / Gerard B. Nash and G. Ed Rainger -- Hydrodynamic interactions between cells on reactive surfaces / Dooyoung Lee and Michael R. King -- Dynamics of platelet aggregation and adhesion to reactive surfaces under flow / Nipa A. Mody and Michael R. King.
Summary This comprehensive work discusses novel biomolecular surfaces that have been engineered to either control or measure cell function at the atomic, molecular, and cellular levels. Each chapter presents real results, concepts, and expert perspectives of how cells interact with biomolecular surfaces, with particular emphasis on interactions within complex mechanical environments such as in the cardiovascular system. In addition, the book provides detailed coverage of inflammation and cellular immune response as a useful model for how engineering concepts and tools may be effectively applied to complex systems in biomedicine.-Accessible to biologists looking for new ways to model their results and engineers interested in biomedical applications -Useful to researchers in biomaterials, inflammation, and vascular biology -Excellent resource for graduate students as a textbook in cell & tissue engineering or cell mechanics courses.
Contents PART I. NEUTROPHIL ADHESION -- Adhesion of flowing neutrophils to model vessel surfaces -- Bond formation during cell compression -- A flow chamber for capillary networks -- Membrane dynamics during neutrophil recruitment -- Hydrodynamic recruitment of cells to reactive surfaces -- PART II: CELL-SUBSTRATE ADHESION -- Cell tensegrity models and cell-substrate interactions -- Use of hydrodynamic shear stress to analyze cell adhesion -- Traction forces exerted by endothelial cells -- Control of endothelial cell adhesion by mechanotransmission -- PART III. ENGINEERED BIOMIMETIC SURFACES -- Realistic atomistic modeling of protein adsorption to ceramic biomaterials -- Cell responses to micro- and nano-topography.
Local Note eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America
Subject Cell interaction.
Cell interaction.
Cell adhesion.
Cell adhesion.
Tissue engineering.
Tissue engineering.
Cell Adhesion -- physiology.
Cell Adhesion Molecules.
Cell Communication.
Tissue Engineering.
Genre/Form Electronic books.
Added Author King, Michael R., 1973-
Other Form: Print version: Principles of cellular engineering. Amsterdam ; Boston : Elsevier Academic Press, ©2006 0123693926 9780123693921 (DLC) 2005025101 (OCoLC)61404511
ISBN 9780123693921
0123693926
9780080539638 (electronic book)
0080539637 (electronic book)