| Description |
1 online resource (xviii, 357 pages, 8 unnumbered pages of plates) : illustrations (some color) |
| Physical Medium |
polychrome |
| Description |
text file |
| Bibliography |
Includes bibliographical references and index. |
| Contents |
Overview of aminoglycosides and enzyme-mediated bacterial resistance: clinical implications / Robert A. Bonomo -- Aminoglycoside antibiotics / Kanchana Majumder [and others] -- Structural aspects of aminoglycoside-modifying enzymes / Gerard D. Wright and Albert M. Berghuis -- Aminoglycoside-modifying enzymes: characteristics, localization, and dissemination / Marcelo E. Tolmasky -- rRNA methylases and resistance to macrolide, lincosamide, streptogramin, ketolide, and oxazolidinone (MLSKO) antibiotics / Marilyn C. Roberts -- [Beta]-lactamases: historical perspectives / Karen Bush and Patricia A. Bradford -- Resistance mediated by penicillin-binding proteins / Malcolm G.P. Page -- Inhibition of class A [beta]-lactamases / Samy O. Meroueh, Jooyoung Cha, And Shahriar Mobashery -- Class B [beta]-lactamases / Gian Maria Rossolini and Jean-Denis Docquier -- Crystal structures of class C [beta]-lactamases: mechanistic implications and perspectives in drug design / C. Bauvois and J. Wouters. |
|
Class D [beta]-lactamases / Franck Danel, Malcolm G.P. Page, and David M. Livermore -- Kinetics of [beta]-lactamases and penicillin-binding proteins / Moreno Galleni and Jean-Marie Frère -- The pharmaceutical industry and inhibitors of bacterial enzymes: implications for drug development / David M. Shlaes, Lefa Alksne, and Steven J. Projan -- [Beta]-lactamase inhibitory proteins / Zhen Zhang and Timothy Palzkill -- Active drug efflux in bacteria / Jürg Dreier -- Overview of dissemination mechanisms of genes coding for resistance to antibiotics / Marcelo E. Tolmasky -- Conjugative transposons / Louis B. Rice -- The dissemination of antibiotic resistance by bacterial conjugation / Virginia L. Waters -- Bacterial toxin-antitoxin systems as targets for the development of novel antibiotics / Juan C. Alonso [and others] -- Integrons and superintegrons / Robert A. Bonomo, Andrea M. Hujer, and Kristine M. Hujer -- The biological cost of antibiotic resistance / Dan I. Andersson [and others]. |
| Summary |
Antibiotic-resistant bacteria, or "superbugs," present an increasingly deadly threat to human health. With chapters from the world's leading researchers and scholars in this field, this comprehensive volume is a vital and timely overview of this critical subject. |
| Local Note |
eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America |
| Subject |
Drug resistance in microorganisms.
|
|
Drug resistance in microorganisms. |
|
Drug resistance in microorganisms -- Genetic aspects.
|
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Drug resistance in microorganisms -- Genetic aspects. |
|
Microbial enzymes.
|
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Microbial enzymes. |
| Genre/Form |
Electronic books.
|
| Added Author |
Bonomo, Robert A., editor.
|
|
Tolmasky, Marcelo, editor.
|
| Other Form: |
Print version: Enzyme-mediated resistance to antibiotics. Washington, D.C. : ASM Press, ©2007 9781555813031 (DLC) 2007002039 (OCoLC)80019936 |
| ISBN |
9781555815615 (electronic book) |
|
1555815618 (electronic book) |
|
9781555813031 |
|
1555813038 |
| Standard No. |
10.1128/9781555815615 |
|
