| Description |
1 online resource (xii, 431 pages) : illustrations |
| Bibliography |
Includes bibliographical references and index. |
| Contents |
1. Introduction: Foot-and-mouth Disease: Much Progress But Still a Lot to Learn / David J. Rowlands -- 2. Genome Organisation, Translation and Replication of Foot-and-mouth Disease Virus RNA / Encarnacion Martinez-Salas and Graham J. Belsham -- 3. Foot-and-mouth Disease Virus Proteinases and Polyprotein Processing / Fiona Tulloch, Garry A. Luke and Martin D. Ryan -- 4. The Foot-and-mouth Disease Virion: Structure and Function / Mauricio G. Mateu -- 5. Foot-and-mouth Disease Virus Receptors: Multiples Gateways to Initiate Infection / Paul Lawrence and Elizabeth Rieder -- 6. The RNA-dependent RNA Polymerase 3D: Structure and Fidelity / Cristina Ferrer-Orta and Nuria Verdaguer -- 7. Quasispecies Dynamics Taught by Natural and Experimental Evolution of Foot-and-mouth Disease Virus / Esteban Domingo, Ignacio de la Higuera, Elena Moreno, Ana I. de Ávila, Rubén Agudo, Armando Arias and Celia Perales -- 8. Clinical Signs and Pathology of Foot-and-mouth Disease / Charles Nfon, Oliver Lung, Carissa Embury-Hyatt and Soren Alexandersen -- 9. Natural Habitats in which Foot-and-mouth Disease Viruses are Maintained / Wilna Vosloo and Gavin R. Thomson -- 10. Innate to Adaptive: Immune Defence Handling of Foot-and-mouth Disease Virus / Kenneth C. McCullough, Margarita Sáiz, and Artur Summerfield -- 11. Laboratory Diagnostic Methods to Support the Surveillance and Control of Foot-and-mouth Disease / Anna Ludi, Valerie Mioulet, Nick J. Knowles and Donald P. King -- 12. Quality Attributes of Current Inactivated Foot-and-mouth Disease (FMD) Vaccines and their Effects on the Success of Vaccination Programmes / Eliana N. Smitsaart and Ingrid E. Bergmann -- 13. Peptide Vaccines Against Foot-and-mouth Disease / E. Blanco, D. Andreu and F. Sobrino -- 14. Control of Foot-and-mouth Disease by Using Replication-defective Human Adenoviruses to Deliver Vaccines and Biotherapeutics / Fayna Diaz-San Segundo, Gisselle Medina, Marvin J. Grubman and Teresa de los Santos -- 15. Antiviral Therapies for Foot-and-mouth Disease / Annebel R. De Vleeschauwer, David J. Lefebvre and Kris De Clercq -- 16. Mathematical Models of the Epidemiology and Control of Foot-and-mouth Disease / Michael J. Tildesley, William J.M. Probert and Mark E.J. Woolhouse -- 17. The Role of International Organizations in the Control of Foot-and-mouth Disease / Bernard Vallat, Joseph Domenech and Alejandro A. Schudel -- 18. Overview of Foot-and-mouth Disease and its Impact as a Re-emergent Viral Infection / Brian W.J. Mahy and Graham J. Belsham. |
| Summary |
This volume provides essential scientific background on FMD and its etiological agent, FMD virus, as well as comprehensive, interdisciplinary and up-to-date information on basic research findings and applied developments contributing to FMD control. The eighteen chapters have been written by leading FMD researchers. Topics include genome organization, translation and replication, virus-coded proteinases, structure of virus particles, cell receptors and host range, the RNA polymerase, quasispecies dynamics and virus evolution, innate and acquired immune responses, and the clinical signs of FMD and its natural habitats. Further chapters deal with various aspects of disease control such as diagnosis, current and new vaccines, antivirals and models of epidemiology. The role of international organizations in FMD control and the impact of FMDV as a re-emergent virus are also addressed. |
| Local Note |
eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America |
| Subject |
Foot-and-mouth disease virus.
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Foot-and-mouth disease virus -- Etiology.
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Foot-and-mouth disease -- Epidemiology.
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Virology.
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Foot-and-mouth disease.
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SCIENCE -- Life Sciences -- Evolution. |
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Foot-and-mouth disease |
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Virology |
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Foot-and-mouth disease -- Epidemiology |
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Foot-and-mouth disease virus |
| Added Author |
Sobrino, Francisco, editor.
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Domingo, Esteban, editor.
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| Other Form: |
Print version: Foot and Mouth Disease Virus. Norfolk, UK : Caister Academic Press, [2017] 9781910190517 1910190519 (OCoLC)951762205 |
| ISBN |
9781910190524 (electronic bk.) |
|
1910190527 (electronic bk.) |
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9781910190517 |
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1910190519 |
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