| Description |
1 online resource (1 PDF file (xiv, 186 pages)) : illustrations |
| Physical Medium |
polychrome |
| Description |
text file |
| Bibliography |
Includes bibliographical references. |
| Summary |
One of the holy grails in biology is the ability to predict functional characteristics from an organism's genetic sequence. Despite decades of research since the first sequencing of an organism in 1995, scientists still do not understand exactly how the information in genes is converted into an organism's phenotype, its physical characteristics. Functional genomics attempts to make use of the vast wealth of data from "-omics" screens and projects to describe gene and protein functions and interactions. A February 2020 workshop was held to determine research needs to advance the field of functional genomics over the next 10-20 years. Speakers and participants discussed goals, strategies, and technical needs to allow functional genomics to contribute to the advancement of basic knowledge and its applications that would benefit society. This publication summarizes the presentations and discussions from the workshop. |
| Funding |
This activity was supported by the National Science Foundation under Award Number 1927620. Any opinions, findings, conclusions, or recommendations expressed in this publication do not necessarily reflect the views of any organization or agency that provided support for the project. |
| Contents |
Front Matter -- 1. Introduction -- 2. The genotypePhenotype challenge -- 3. Case studies on building functional genomics tools in diverse systems -- 4. Understanding the contributions of non-protein-coding DNA to phenotype -- 5. Advancing research on the environmental regulation of gene function -- 6. Predicting current and future sources of variation in quantitative traits -- 7. Interpreting and validating results from high-throughput screening approaches -- 8. Large databases and consortia -- 9. Big-picture challenges in research, education, and training -- 10. Future of functional genomics -- References -- Appendix A: Statement of task -- Appendix B: Workshop agenda -- Appendix C: Planning committee biographies -- Appendix D: Speaker biographies -- Appendix E: Acronyms and abbreviations. |
| Local Note |
eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America |
| Subject |
Functional genomics -- Congresses.
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Functional genomics. |
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Genes -- Congresses.
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Genes. |
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Phenotype -- Congresses.
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Phenotype. |
| Genre/Form |
Conference papers and proceedings.
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Electronic books.
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Congress.
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Conference papers and proceedings.
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| Added Author |
Moss, Steven M., rapporteur.
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Sharples, Frances Ellen, rapporteur.
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National Academies of Sciences, Engineering, and Medicine (U.S.). Board on Life Sciences, issuing body.
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Next Steps for Functional Genomics (Workshop) (2020 : Washington, D.C.)
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| Other Form: |
Print version: 0309676738 9780309676731 (OCoLC)1192309941 |
| ISBN |
9780309676731 |
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0309676738 |
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9780309676748 (electronic book) |
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0309676746 (electronic book) |
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9780309676762 (electronic book) |
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0309676762 (electronic book) |
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