| Edition |
Second edition. |
| Description |
1 online resource (pages) |
| Physical Medium |
polychrome |
| Description |
text file |
| Bibliography |
Includes bibliographical references and index. |
| Contents |
Sex differences in disease -- Evolution of the human sex chromosomes and a portrait of the human X -- X chromosome dosage compensation : an overview -- The discovery of X chromosome inactivation -- Experimental models for X inactivation studies -- Theme 1 : the initial step : creating the active and inactive X -- Theme 2 : subsequent steps : spreading and maintaining inactivation -- Variations 1 : evolution of the X inactivation center -- Variations 2 : stability of the inactive X -- Variations 3 : choice of active X -- The single active X -- Mosaicism -- Epimutations, chromatin disorders and sex differences in phenotype -- Determinants of female phenotypes. |
| Summary |
Women can be described as genetic mosaics because they have two distinctly different types of cells throughout their bodies. Unlike males, who have one X chromosome, females have two X chromosomes in every cell. Much has been written about the Y chromosome and its role in inducing maleness. This is the only book about the X chromosome as a key to female development and the role of X-related factors in the etiology of sex differences in human disease. This new edition reflects research advances from the six years since the widely praised first edition. New advances include knowledge of species differences in mammalian X inactivation processes and silencing of the inactive X chromosome. |
| Local Note |
eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America |
| Subject |
X chromosome.
|
|
X chromosome. |
|
Mosaicism.
|
|
Mosaicism. |
|
Genetic sex determination.
|
|
Genetic sex determination. |
|
Sex-linkage (Genetics)
|
|
Sex-linkage (Genetics) |
| Genre/Form |
Electronic books.
|
|
Electronic book.
|
| Subject |
Mosaicism involving "sex" chromosomes. |
| Other Form: |
Print version: Migeon, Barbara R. Females are mosaics. Second edition 9780199927531 (DLC) 2013017154 (OCoLC)841556714 |
| ISBN |
9780199927548 (electronic book) |
|
0199927545 (electronic book) |
|
9780199927531 |
|
0199927537 |
|
