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Title Handbook of the biology of aging / editors, Edward J. Masoro and Steven N. Austad.

Publication Info. Amsterdam ; Boston : Elsevier Academic Press, [2006]
©2006

Item Status

Edition 6th ed.
Description 1 online resource (xx, 660 pages) : illustrations.
Physical Medium polychrome
Description text file
Series The handbooks of aging
Handbooks of aging.
Bibliography Includes bibliographical references and indexes.
Contents Section I. Conceptual and technical issues. Reliability theory of aging and longevity / Leonid A. Gavrilov and Natalia S. Gavrilova -- Are age-associated diseases an integral part of aging? / Edward J. Masoro -- Dietary restriction, hormesis, and small molecule mimetics / David A. Sinclair and Konrad T. Howitz -- Hematopoietic stem cells, aging, and cancer / Deborah R. Bell and Gary Van Zant -- Mitochondria: a critical role in aging / Tamara R. Golden [and others] -- P53 and mouse aging models / Catherine Gatza [and others] -- Complex genetic architecture of Drosophila longevity / Trudy F.C. Mackay [and others] -- Evolutionary biology of aging: future directions / Daniel E.L. Promislow, Kenneth M. Fedorka, and Joep M.S. Burger -- Senescence in wild populations of mammals and birds / Anja K. Brunet-Rossinni and Steven N. Austad -- Biodemography of aging and age-specific mortality in Drosophila melanogaster / James W. Curtsinger, Natalia S. Gavrilova, and Leonid A. Gavrilov -- Microarray analysis of gene expression changes in aging / F. Noel Hudson [and others] -- Computer modeling in the study of aging / Thomas B.L. Kirkwood [and others] -- Section II. Non-mammalian models. Dissecting the processes of aging using the nematode Caenorhabditis elegans / Samuel T. Henderson, Shane L. Rea, and Thomas E. Johnson -- Genetic manipulation of life span in Drosophila melanogaster / Daniel Ford and John Tower -- Juvenile and steroid hormones in Drosophila melanogaster longevity / Meng-Ping Tu, Thomas Flatt, and Marc Tatar -- A critical evaluation of nonmammalian models for aging research / Steven N. Austad and Andrei Podlutsky -- Section III. Mammalian models. Differential aging among skeletal muscles / Roger J.M. McCarter -- Aging, body fat, and carbohydrate metabolism / Marielisa Rincon, Radhika Muzumdar, and Nir Barzilai -- Growth and aging: why do big dogs die young? / Richard A. Miller and Steven N. Austad -- Growth hormone, insulin-like growth factor-1, and the biology of aging / Christy S. Carter and William E. Sonntag -- Aging of the female reproductive system / Phyllis M. Wise.
Summary The Handbook of the Biology of Aging, Sixth Edition, provides a comprehensive overview of the latest research findings in the biology of aging. Intended as a summary for researchers, it is also adopted as a high level textbook for graduate and upper level undergraduate courses. The Sixth Edition is 20% larger than the Fifth Edition, with 21 chapters summarizing the latest findings in research on the biology of aging. The content of the work is virtually 100% new. Though a selected few topics are similar to the Fifth Edition, these chapters are authored by new contributors with new information. The majority of the chapters are completely new in both content and authorship. The Sixth Edition places greater emphasis and coverage on competing and complementary theories of aging, broadening the discussion of conceptual issues. Greater coverage of techniques used to study biological issues of aging include computer modeling, gene profiling, and demographic analyses. Coverage of research on Drosophilia is expanded from one chapter to four. New chapters on mammalian models discuss aging in relation to skeletal muscles, body fat and carbohydrate metabolism, growth hormone, and the human female reproductive system. Additional new chapters summarize exciting research on stem cells and cancer, dietary restriction, and whether age related diseases are an integral part of aging. The Handbook of the Biology of Aging, Sixth Edition is part of the Handbooks on Aging series, including Handbook of the Psychology of Aging and Handbook of Aging and the Social Sciences, also in their 6th editions.
Local Note eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America
Subject Aging -- Physiological aspects -- Handbooks, manuals, etc.
Aging -- Physiological aspects.
Genre/Form Handbooks and manuals.
Subject Aging -- physiology.
Genre/Form Electronic books.
Handbooks and manuals.
Added Author Masoro, Edward J.
Austad, Steven N., 1946-
Added Title Biology of aging
Other Form: Print version: Handbook of the biology of aging. 6th ed. Amsterdam ; Boston : Elsevier Academic Press, ©2006 0120883872 9780120883875 (DLC) 2005023985 (OCoLC)61453894
ISBN 9780080491400 (electronic book)
0080491405 (electronic book)
9780120883875
0120883872
0120883872 (alkaline paper)