| Description |
1 online resource (250 pages) |
| Physical Medium |
polychrome |
| Description |
text file |
| Note |
Description based upon print version of record. |
| Contents |
Cover -- Title -- Copyright -- End User License Agreement -- Contents -- Preface -- CONSENT FOR PUBLICATION -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENTS -- How to Build a Drug: Exercises Based on the Concept of Retrosynthetic Analysis -- INTRODUCTION -- PROTECTIVE GROUPS -- EXERCISES 1 TO 4 -- RETROSYNTHETIC ANALYSIS -- EXERCISE 1 -- TWO SYNTHONS = DRUG -- Example -- Answer -- EXERCISES -- Answers -- EXERCISE 2 -- EPOXIDES -- Example -- Answer -- EXERCISES -- Answers -- EXERCISE 3 -- PIPERAZINE AND RELATED SUBSTANCES -- Examples -- Answers -- EXERCISES -- Answers -- EXERCISE 4 -- ALDEHYDES |
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Examples -- Answers -- EXERCISES -- Answers -- CONCLUSION OF THE EXERCISES 1 TO 4 (RETROSYNTHETIC ANALYSIS) -- Organizing Synthetic Routes and Identifying Reagents -- EXERCISES 5 TO 8 -- INTRODUCTION -- EXERCISE 5 -- ORGANIZING SYNTHETIC ROUTES -- Example -- Answer -- EXERCISES -- RUTHENIUM AND ITS COMPLEXES AS OXIDANTS -- MECHANISM OF WITTIG-HORNER REACTION -- EXERCISE 6 -- IDENTIFYING REAGENTS -- Example -- Answer -- EXERCISES -- Answers -- CONCLUSION OF THE EXERCISES 5 AND 6 (ORGANIZING SYNTHETIC ROUTES AND IDENTIFYING REAGENTS) -- Identifying Drug Structure and Completing the Gaps |
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EXERCISE 7 -- IDENTIFYING DRUG STRUCTURE -- Examples -- Answers -- EXERCISES -- Answers -- EXERCISE 8 -- COMPLETING THE GAPS -- Example -- Answer -- EXERCISES -- Answers -- CONCLUSION OF EXERCISES 7 AND 8 (IDENTIFYING DRUG STRUCTURE AND COMPLETING THE GAPS) -- BIBLIOGRAPHIC DATA OF EXERCISES 1 TO 9 -- Heteroaromatic Substances -- FIVE-MEMBERED RINGS -- SIX-MEMBERED RINGS -- FUSED SYSTEMS -- Example -- Answer -- MECHANISM OF REACTION -- EXERCISES -- Answers -- CONCLUSION -- Hydrazine and its Derivatives -- INTRODUCTION -- Example -- Answer -- EXERCISES -- Answers -- CONCLUSION -- Nitriles |
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INTRODUCTION -- Example -- Answer -- EXERCISES -- Answers -- CONCLUSION -- Combinatorial Chemistry -- INTRODUCTION -- Example -- Answer -- MECHANISM OF REACTION -- EXERCISES -- Answers -- CONCLUSION -- REFERENCE -- Multicomponent Reaction (MCR) -- INTRODUCTION -- Example -- Answer -- Important Note -- EXERCISES -- Answers -- CONCLUSION -- Click Chemistry -- INTRODUCTION -- Example -- Answer -- EXERCISES -- Answers -- CONCLUSION -- SUGGESTIONS FOR READING -- Fluorine in Drug Discovery -- INTRODUCTION -- FLUORINATION REAGENTS |
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Nucleophilic Fluorination for the Introduction of Fluorine Atom NaF, KF, HF, and Bu4NF -- Diethylaminosulfur Trifluoride (DAST) -- Nucleophilic Fluorination for the Introduction of the Trifluoromethyl Group -- Eletrophilic Fluorination for the Introduction of Fluorine Atoms -- Electrophilic Fluorination for the Introduction of the Trifluoromethyl Group -- Radical Fluorination -- CLASSICAL EXAMPLES OF THE IMPORTANCE OF FLUORINE IN DRUG DEVELOPMENT -- Fluoroquinolone -- Sitagliptin -- Odanacatib -- Celecoxib -- Example -- Answer -- EXERCISES -- Answers -- CONCLUSION -- REFERENCES |
| Note |
List of Journals. |
| Local Note |
eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America |
| Subject |
Organic compounds -- Synthesis.
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Organic compounds -- Synthesis. |
| Genre/Form |
Electronic books.
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| Other Form: |
Print version: Nora, Marcus VinÃcius Exercises in Organic Synthesis Based on Synthetic Drugs Singapore : Bentham Science Publishers,c2020 9789811487545 |
| ISBN |
9811487561 |
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9789811487569 (electronic book) |
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