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Title Microbial glycobiology : structures, relevance and applications / editor-in-chief, Anthony P. Moran ; editors, Otto Holst, Patrick J. Brennan, Mark von Itzstein.

Publication Info. Amsterdam ; Boston : Academic Press/Elsevier, [2009]
©2009

Item Status

Edition 1st ed.
Description 1 online resource (xviii, 1000 pages, 16 unnumbered pages of plates) : illustrations (some color)
Physical Medium polychrome
Description text file
Bibliography Includes bibliographical references and index.
Contents Part I. Microbial glycolipids, glyoproteins and glycopolymers€ 1. Overview of the glycosylated components of the bacterial cell wall€€ 2. Bacterial cell wall envelope peptidoglycan€€ 3. Core oligosaccharide and lipid A components of lipopolysaccharides€€ 4. O-Specific polysaccharides of Gram-negative bacteria€€ 5. Teichoic acids, lipoteichoic acids, and related cell wall glycopolymers of Gram-positive bacteria€€ 6. Bacterial capsular polysaccharides and exopolysaccharides€€ 7. Bacterial surface layer glycoproteins and "non-classical" secondary cell wall polymers€€ 8. Glycosylation of bacterial and archaeal flagellins€€ 9. Glycosylated components of the mycobacterial cell wall: structure and function€€ 10. Glycoconjugate structure and function in fungal cell walls€€ 11. Cytoplasmic carbohydrate molecules: trehalose and glycogen€€ 12. Glycosylated compounds of parasitic protozoa€€ 13. Analytical approaches towards the structural characterization of microbial wall glycopolymers€€ 14. Single-molecule characterization of microbial polysaccharides€€ 15. Viral surface glycoproteins in carbohydrate recognition: structure and modeling€Part II. Synthesis of microbial glycosylated components; A. Biosynthesis and biosynthetic processes€ 16. Biosynthesis of bacterial peptidoglycan€€ 17. Biosynthesis and membrane assembly of lipid A€€ 18. Biosynthesis of O-antigen chains and assembly€€ 19. Biosynthesis of cell wall teichoic acid polymers€€ 20. Biosynthesis and assembly of capsular polysaccharides€€ 21. Biosynthesis of the mycobacterial cell envelope components€€ 22. Biosynthesis of fungal and yeast glycans€B. Chemical synthesis€€ 23. Chemical synthesis of bacterial lipid A€€ 24. Chemical synthesis of the core oligosaccharide of bacterial lipopolysaccharide€€ 25. Chemical synthesis of lipoichoic acid and derivatives€€ 26. Chemical synthesis of parasitic glycoconjugates and phosphoglycans€ Part III. Microbe-host glycosylated interactions€€ 27. Bacterial lectin-like interactions in cell recognition and adhesion€€ 28. Lectin-like interactions in virus-cell recognition: human immunodeficiency virus and C-type lectin interactions€€ 29. Sialic acid-specific microbial lectins€€€ 30. Bacterial toxins and their carbohydrate receptors at the host-pathogen interface€€ 31. Toll-like receptor recognition of lipoglycans, glycolipids and lipopeptides€€ 32. NOD receptor recognition of peptidoglycan€€ 33. Microbial interaction with mucus and mucins€€ 34. Mannose-fucose recognition by DC-SIGN€€ 35. Host surfactant proteins in microbial recognition€€ 36. T-cell recognition of microbial lipoglycans and glycolipids€ Part IV. Biological relevance of microbial glycosylated components; A. Environmental relevance€€ 37. Extracellular polymeric substances in microbial biofilms€€ 38. Physico-chemical properties of microbial glycopolymers€€ 39. Microbial biofilm-related polysaccharides in biofouling and corrosion€€ 40. Microbial glycosylated components in plant disease€€B. Medical relevance€€ 41. Antigenic variation of microbial surface glycosylated molecules€€ 42. Phase variation of bacterial surface glycosylated molecules in immune evasion€€ 43. Molecular mimicry of host glycosylated structures by bacteria€€ 44. Role of microbial glycosylation in host cell invasion€ Part V. Biotechnological and medical applications€€ 45. Exopolysaccharides produced by lactic acid bacteria in food and probiotic applications€€ 46. Industrial exploitation by genetic engineering of bacterial glycosylation systems€€ 47. Glycomimetics as inhibitors in anti-infection therapy€€ 48. Bacterial polysaccharide vaccines: glycogonjugates and peptide-mimetics€€ 49. Immunomodulation by zwitterionic polysaccharides€€ 50. Future potential of glycomics in microbiology and infectious diseases€
Access Use copy Restrictions unspecified MiAaHDL
Summary This book presents in an easy-to-read format a summary of the important central aspects of microbial glycobiology, i.e. the study of carbohydrates as related to the biology of microorganisms. Microbial glycobiology represents a multidisciplinary and emerging area with implications for a range of basic and applied research fields, as well as having industrial, medical and biotechnological implications. Key Features and Benefits * Individual chapters provided by leading international scientists in the field yield insightful, concise and stimulating reviews. - Provides researchers with an overview and synthesis of the latest research * Each chapter begins with a brief 200 word Summary/Abstract detailing the topic and focus of the chapter, as well as the concepts to be addressed. - Allows researchers to see at a glance what each chapter will cover * Each chapter includes a Research Focus Box - Identifies important problems that still need to be solved and areas that require further investigation.
Reproduction Electronic reproduction. [S.l.] : HathiTrust Digital Library, 2010. MiAaHDL
System Details Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. http://purl.oclc.org/DLF/benchrepro0212 MiAaHDL
Processing Action digitized 2010 HathiTrust Digital Library committed to preserve MiAaHDL
Local Note eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America
Subject Pathogenic microorganisms -- Identification.
Pathogenic microorganisms -- Identification.
Glycomics.
Glycomics.
Glycomics -- methods.
Microbiological Techniques.
Genre/Form Electronic books.
Guidebooks.
Added Author Moran, Anthony P.
Holst, Otto.
Brennan, Patrick J. Ph. D.
Itzstein, Mark von.
Other Form: Print version: Microbial glycobiology. 1st ed. Amsterdam ; Boston : Academic Press/Elsevier, ©2009 9780123745460 (OCoLC)432405794
ISBN 9780080923246 (electronic book)
0080923240 (electronic book)
9780123745460
0123745462
Standard No. 9786612737428