Title Clinical applications of mifepristone (RU 486) and other antiprogestins : assessing the science and recommending a research agenda / Committee on Antiprogestins: Assessing the Science, Division of Health Promotion and Disease Prevention, Institute of Medicine ; Molla S. Donaldson [and others], editors.

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Washington, D.C. : National Academy Press, 1993.

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Description	1 online resource (xi, 288 pages) : illustrations
Physical Medium	polychrome
Description	text file
Note	"Support for this project was provided by a grant from the Henry J. Kaiser Family Foundation, Menlo Park, California."--Title page verso.
	Committee chairman: Leslie Z. Benet.
Bibliography	Includes bibliographical references and index.
Contents	Background and historical perspectives -- IOM report -- Cross-cutting recommendations -- Uses of antiprogestins: the reproductive cycle -- Contraception -- Post-coital contraception -- Menses induction -- Uses of antiprogestins: the reproductive cycle -- Pregnancy termination during the first trimester -- Pregnancy termination during the second trimester -- Cervical ripening -- Labor induction in late pregnancy -- Other therapeutic uses of antiprogestins -- Endometriosis -- Uterine leiomyomas (fibroids) -- Breast cancer -- Meningiomas -- Antiglucocorticoid effects of antiprogestins -- Glucocorticoid function -- Therapeutic use of mifepristone (RU 486) as an antiglucocorticoid -- Adverse antiglucocorticoid effects of antiprogestins -- Animals as models for studying antiprogestins -- Agenda for the IOM workshop "Antiprogestins: Assessing the Science" -- Background papers and presentations (in order of presentation at IOM workshop) -- 1993: RU 486: a decade on today and tomorrow / Etienne-Emile Baulieu.
	(cont) Overview and background: mechanism of action of antiprogestins / Nancy L. Weigel -- Use of antiprogestins in the reproductive cycle / Lynnette Kaye Nieman -- Potential contraceptive effects of antigestogens / David T. Baird -- Use of antiprogestins before 63 days of amenorrhea / Marc Bygdeman -- Uses of antiprogestins after 63 days of amenorrhea / Ancre Ulmann and Louise Silvestre -- Comments on session II -- David Grimes -- Use of antiprogestins in the management of endometriosis and leiomyoma / Samuel S.C. Yen -- Antiprogestins and the treatment of breast cancer / Kathryn B. Horwitz -- Uses of RU 486 as an antiglucocorticoid / Lynnette Kaye Nieman -- Primate models for the study of antiprogestins in reproductive medicine / Gary D. Hodgen -- Antiprogestogens: perspectives from a global research program / P.F.A. Van Look and H. von Hertzen -- Observers at the workshop on antiprogestins.
Local Note	eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America
Subject	Mifepristone -- Research.
	Mifepristone.
	Research.
	Abortifacients -- Research.
	Abortifacients.
	Progesterone -- Antagonists -- Research.
	Progesterone -- Antagonists.
	Mifepristone.
	Abortifacient Agents.
	Progesterone -- antagonists & inhibitors.
Genre/Form	Electronic books.
Added Author	Benet, Leslie Z.
	Donaldson, Molla S.
	Institute of Medicine (U.S.). Committee on Antiprogestins: Assessing the Science.
	Institute of Medicine (U.S.). Division of Health Promotion and Disease Prevention.
Other Form:	Print version: Clinical applications of mifepristone (RU 486) and other antiprogestins. Washington, D.C. : National Academy Press, 1993 0309049490 (DLC) 93085360 (OCoLC)28761657
ISBN	0585024782 (electronic book)
	9780585024783 (electronic book)
	0309049490
	9780309049498 (paperback)

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