| Description |
1 online resource (xli, 446 pages) : illustrations (chiefly color). |
| Physical Medium |
polychrome |
| Description |
text file |
| Series |
Progress in gene therapy ; v. 3
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Progress in gene therapy ; v. 3.
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| Bibliography |
Includes bibliographical references and index. |
| Contents |
Introduction. Toward a universal platform for autologous stem cell gene therapy / Roger Bertolotti -- Long-term stem cell gene therapy: from current clinical random-integration achievements to stem cell gene targeting/cybridization -- I. From pioneering clinical retroviral gene therapy to experimental site-specific integrative gene therapy. 1. Stem cell gene therapy for ADA-deficiency without myelopreparative conditioning / Makoto Otsu and Tadashi Ariga. 2. Targeted insertion of transgene into a specific site on Chromosome 19 by using Adeno-Associated Virus integration machinery / Masashi Urabe [and others] 3. Herpes Simplex Virus Type 1/Adeno-Associated Virus Hybrids as site-specific integrating vectors / Cornel Fraefel [and others] -- II. Stem cell gene targeting/cybridization: toward endonuclease-boosted gene repair/alteration, custom site-specific integrative gene therapy and transmitochondrial therapy/rejuvenation. 4. Endonuclease-boosted gene targeting and cybridization for long-term stem cell gene therapy / Roger Bertolotti. 5. Cell-Free Protein-evolution systems for engineering of novel sequence-specific DNA-binding and -modifying activities / Armin Sepp, Farid Ghadessy and Yen Choo. 6. Advances in engineering homing endonucleases for gene targeting: ten years after structures / Barry L. Stoddard, Andrew M. Scharenberg and J. Monnat, Jr. 7. Gene targeting mediated by helper-dependent adenoviral vectors / Kohnosuke Mitani -- Adult pluripotent stem cells: emerging stem cell/gene therapy breakthrough. 8. Multipotent progenitor cells: a new era in stem cell mediated gene therapy? -- Cancer stem cell gene therapy. I. Cancer stem cells as breakthrough targets of cancer gene therapy. 9. Leukemia stem cells, a pioneering paradigmatic model / Daniel J. Pearce and Dominique Bonnet. 10. Mammary stem cells / Mary Shackleton [and others] 11. Human brain tumor stem cells / Sara G.M. Piccirillo and Angelo L. Vescovi. 12. CD44 as a functional cancer stem cell marker and a potential therapeutic target / Lubna Patrawala and Dean G. Tang -- II. Armed stem cells as tumor-homing vectors for cancer gene therapy. 13. Neural stem cell-mediated therapy of primary and metastatic solid tumors / Joseph Najbauer [and others] 14. Antitumor activity of adenovirally transduced CD34+ cells expressing membrane-bound TRAIL / Carmelo Carlo-Stella [and others] 15. Mesenchymal stem cells as vehicles for delivering therapeutics and oncolytic viruses / Larisa Pereboeva and Justin Roth. |
| Local Note |
eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America |
| Subject |
Stem cells -- Therapeutic use.
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Stem cells. |
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Stem cells -- Transplantation.
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Stem cells -- Transplantation. |
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Gene therapy.
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Gene therapy. |
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Cancer -- Gene therapy.
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Cancer -- Gene therapy. |
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Autotransplantation.
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Autotransplantation. |
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Genetic Therapy. |
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Stem Cells. |
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Neoplastic Stem Cells. |
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Regenerative Medicine. |
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Stem Cell Transplantation. |
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Transplantation, Autologous. |
| Genre/Form |
Electronic books.
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| Added Author |
Bertolotti, R. (Roger)
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Ozawa, Keiya, 1953-
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| Other Form: |
Print version: Autologous and cancer stem cell gene therapy. Hackensack, NJ : World Scientific, ©2008 9789812775863 9812775862 (DLC) 2007043710 (OCoLC)176925204 |
| ISBN |
9789812775870 (electronic book) |
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9812775870 (electronic book) |
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9789812775863 (hardcover ; alkaline paper) |
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9812775862 (hardcover ; alkaline paper) |
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