Acetate : versatile building block of biology and chemistry / [edited by] David A. Sanders (Markey Center for Structural Biology, Department of Biological Sciences, Purdue University, West Lafayette, IN, USA).
Acetic acid and its conjugate base acetate are amazing molecules. The combination of a methyl group and a carboxylic acid/carboxylate makes acetic acid/acetate the primordium of complex organic molecules. Acetic acid is uncommon among common biological carbon sources besides gases in that it can freely diffuse across membranes. The central role of acetate in the global carbon cycle and the origin and evolution of life on earth are expertly portrayed by Ferry. Fermentation reduces biomass predominantly to acetate. Acetate is the metabolic currency between the bacteria and archaea domains of lif.
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