| Description |
1 online resource (xiii, 122 pages) : color illustrations |
|
text file |
| Bibliography |
Includes bibliographical references (pages 90-94). |
| Contents |
Introduction to precision medicine and animal models -- Existing precision medicine initiatives -- The promise and perils of animal models -- Reproducibility and predictivity -- In vitro alternatives to animal models -- Assessing safety and toxicology -- Patient perspectives -- Reflections on the workshop -- References. |
| Summary |
"Precision medicine is focused on the individual and will require the rapid and accurate identification and prioritization of causative factors of disease. To move forward and accelerate the delivery of the anticipated benefits of precision medicine, developing predictable, reproducible, and reliable animal models will be essential. In order to explore the topic of animal-based research and its relevance to precision medicine, the National Academies of Sciences, Engineering, and Medicine convened a 2-day workshop on October 5 and 6, 2017. The workshop was designed to focus on the development, implementation, and interpretation of model organisms to advance and accelerate the field of precision medicine. Participants examined the extent to which next-generation animal models, designed using patient data and phenotyping platforms targeted to reveal and inform disease mechanisms, will be essential to the successful implementation of precision medicine. This publication summarizes the presentations and discussions from the workshop"--Publisher's description. |
| Local Note |
eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America |
| Subject |
Animal models in research -- Congresses.
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Animal models in research. |
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Precision medicine -- Congresses.
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Precision medicine. |
| Genre/Form |
Congress.
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Electronic books.
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Conference papers and proceedings.
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Conference papers and proceedings.
|
| Added Author |
Anestidou, Lida, 1965- rapporteur.
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National Academies of Sciences, Engineering, and Medicine (U.S.). Roundtable on Science and Welfare in Laboratory Animal Use, issuing body.
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Advancing Disease Modeling in Animal-Based Research in Support of Precision Medicine (Workshop) (2017 : Washington, D.C.), author.
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| Other Form: |
Print version: Forstag, Erin Hammers. Advancing disease modeling in animal-based research in support of precision medicine : proceedings of a Workshop. Washington, D.C. : National Academies Press, ©2018 9780309471169 |
| ISBN |
9780309471190 (electronic book) |
|
0309471192 (electronic book) |
|
9780309471176 |
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0309471176 |
|
9780309471169 (paperback) |
|
0309471168 (paperback) |
| Standard No. |
10.17226/25002 |
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