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Title Nutritional Signaling Pathway Activities in Obesity and Diabetes.

Publication Info. Cambridge : Royal Society of Chemistry, 2020.

Item Status

Description 1 online resource (354 pages).
text file
Series Food chemistry, function and analysis ; 24
Food chemistry, function and analysis ; no. 24.
Contents Cover -- Half-title -- Series information -- Title page -- Copyright information -- Preface -- Table of contents -- Chapter 1 Diabetes and Obesity: An Overview of Nutritional Effects -- 1.1 Introduction -- 1.2 Mechanisms of Insulin Resistance and Metabolic Syndrome -- 1.3 Prevention Trials -- 1.4 Adherence -- 1.5 Dietary Components Affecting T2D -- 1.5.2 Fiber -- 1.5.3 Glycemic Index and Load -- 1.6 Dietary Interventions in T2D -- 1.6.1 Mediterranean Diet -- 1.6.2 The New Nordic Diet -- 1.6.3 The Ornish Diet -- 1.6.4 Ketogenic Diet -- 1.7 Micronutrients -- 1.7.1 Chromium -- 1.7.2 Selenium
1.7.3 Vitamin D -- 1.7.4 Cinnamon -- 1.8 Plant Alkaloids -- 1.9 Future Directions -- References -- Chapter 2 Maternal Nutrition and the Risk of Obesity and Diabetes in the Offspring -- 2.1 Introduction -- 2.2 Evidence from Epidemiology and Human Studies -- 2.3 Evidence from Experimental Animal Models -- 2.3.1 Global Nutrient Restriction -- 2.3.2 Protein Restriction -- 2.3.3 Maternal Obesity -- 2.3.4 Micronutrient Deficiencies -- 2.3.5 Other Models -- 2.4 Epigenetic Mechanisms -- 2.5 Intervention Strategies -- 2.6 Conclusions -- References
Chapter 3 Lessons Learned from Recent Clinical Trials Targeting Diets to Treat and Prevent Obesity and Diabetes -- 3.1 Introduction -- 3.2 Current Issues in Diabetes and Obesity Research -- 3.3 Results from Reviews on Obesity and Diabetes -- 3.3.1 Limitations of Interpreting Review Data -- 3.3.2 Low-fat Diets -- 3.3.2.1 Clinical Trials -- 3.3.2.2 Potential Mechanisms of Low-fat Diets -- 3.3.3 Low-carbohydrate Diets -- 3.3.3.1 Clinical Trials -- 3.3.3.2 Potential Mechanisms of Low-carbohydrate Diets -- 3.4 Challenges with Diets as Interventions and Suggestions for the Future -- 3.5 Summary
Acknowledgement -- References -- Chapter 4 Nutritional Regulation of Inflammation in Obesity and Diabetes -- 4.1 Introduction -- 4.2 Nutritional Regulation of Adipocytes in Obesity and Type 2 Diabetes -- 4.3 Nutritional Regulation of Nutrition on Immune Cells in Obesity and Type 2 Diabetes -- 4.4 Nutritional Regulation of Inflammatory Signaling Pathways in Obesity and Type 2 Diabetes -- 4.4.1 5' Adenosine Monophosphate-activated Protein Kinase (AMPK) as a Central Energy Sensor -- 4.4.2 NF-.B Signaling Pathways as an Inflammatory Switch -- 4.4.3 AMPK-SIRT1-NF-.B Signaling Pathway
4.4.4 AMPK-FOXOs-NF-.B Signaling Pathway -- 4.4.5 PGC-1a/PPAR.-NF-.B Signaling Pathway -- 4.4.6 mTOR Signaling Pathway -- 4.4.7 The Roles of TLRs and NLRPs in Inflammation -- 4.5 Conclusion -- References -- Chapter 5 The Interaction of Nutrition with Nuclear Receptors in Obesity and Diabetes -- 5.1 Introduction -- 5.2 Metabolic Nuclear Receptors -- 5.2.1 The Interaction of Nutrition with Nuclear Receptors -- 5.2.2 Interaction of Nutrients with Metabolic Nuclear Receptors in Different Tissues During Obesity and Diabetes -- 5.3 Intestine
5.3.1 Physiological Role of FXR on Bile Acid (BA) Homeostasis and Hormone Secretion in the Intestine
Summary This book disseminates the cutting-edge knowledge pertaining to nutritional signaling activities in obesity and diabetes, including the regulatory mechanisms and perspectives of nutritional interventions for disease prevention.
Local Note eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America
Subject Metabolism.
Metabolism.
Metabolism -- Disorders.
Metabolism -- Disorders.
Nutrition.
Nutrition.
Cellular signal transduction.
Cellular signal transduction.
Genre/Form Electronic books.
Added Author Cheng, Zhiyong.
Other Form: Print version: Cheng, Zhiyong Nutritional Signaling Pathway Activities in Obesity and Diabetes Cambridge : Royal Society of Chemistry,c2020 9781788015578
ISBN 9781839160608 (electronic book)
1839160608 (electronic book)
9781839160615 (ebook)
1839160616
9781788015578
1788015576