| Description |
1 online resource (354 p.). |
| Series |
Food chemistry, function and analysis ; 24
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Food chemistry, function and analysis ; no. 24.
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| Contents |
Cover -- Half-title -- Series information -- Title page -- Copyright information -- Preface -- Table of contents -- Chapter 1 Diabetes and Obesity: An Overview of Nutritional Effects -- 1.1 Introduction -- 1.2 Mechanisms of Insulin Resistance and Metabolic Syndrome -- 1.3 Prevention Trials -- 1.4 Adherence -- 1.5 Dietary Components Affecting T2D -- 1.5.2 Fiber -- 1.5.3 Glycemic Index and Load -- 1.6 Dietary Interventions in T2D -- 1.6.1 Mediterranean Diet -- 1.6.2 The New Nordic Diet -- 1.6.3 The Ornish Diet -- 1.6.4 Ketogenic Diet -- 1.7 Micronutrients -- 1.7.1 Chromium -- 1.7.2 Selenium |
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1.7.3 Vitamin D -- 1.7.4 Cinnamon -- 1.8 Plant Alkaloids -- 1.9 Future Directions -- References -- Chapter 2 Maternal Nutrition and the Risk of Obesity and Diabetes in the Offspring -- 2.1 Introduction -- 2.2 Evidence from Epidemiology and Human Studies -- 2.3 Evidence from Experimental Animal Models -- 2.3.1 Global Nutrient Restriction -- 2.3.2 Protein Restriction -- 2.3.3 Maternal Obesity -- 2.3.4 Micronutrient Deficiencies -- 2.3.5 Other Models -- 2.4 Epigenetic Mechanisms -- 2.5 Intervention Strategies -- 2.6 Conclusions -- References |
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Chapter 3 Lessons Learned from Recent Clinical Trials Targeting Diets to Treat and Prevent Obesity and Diabetes -- 3.1 Introduction -- 3.2 Current Issues in Diabetes and Obesity Research -- 3.3 Results from Reviews on Obesity and Diabetes -- 3.3.1 Limitations of Interpreting Review Data -- 3.3.2 Low-fat Diets -- 3.3.2.1 Clinical Trials -- 3.3.2.2 Potential Mechanisms of Low-fat Diets -- 3.3.3 Low-carbohydrate Diets -- 3.3.3.1 Clinical Trials -- 3.3.3.2 Potential Mechanisms of Low-carbohydrate Diets -- 3.4 Challenges with Diets as Interventions and Suggestions for the Future -- 3.5 Summary |
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Acknowledgement -- References -- Chapter 4 Nutritional Regulation of Inflammation in Obesity and Diabetes -- 4.1 Introduction -- 4.2 Nutritional Regulation of Adipocytes in Obesity and Type 2 Diabetes -- 4.3 Nutritional Regulation of Nutrition on Immune Cells in Obesity and Type 2 Diabetes -- 4.4 Nutritional Regulation of Inflammatory Signaling Pathways in Obesity and Type 2 Diabetes -- 4.4.1 5' Adenosine Monophosphate-activated Protein Kinase (AMPK) as a Central Energy Sensor -- 4.4.2 NF-.B Signaling Pathways as an Inflammatory Switch -- 4.4.3 AMPK-SIRT1-NF-.B Signaling Pathway |
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4.4.4 AMPK-FOXOs-NF-.B Signaling Pathway -- 4.4.5 PGC-1a/PPAR.-NF-.B Signaling Pathway -- 4.4.6 mTOR Signaling Pathway -- 4.4.7 The Roles of TLRs and NLRPs in Inflammation -- 4.5 Conclusion -- References -- Chapter 5 The Interaction of Nutrition with Nuclear Receptors in Obesity and Diabetes -- 5.1 Introduction -- 5.2 Metabolic Nuclear Receptors -- 5.2.1 The Interaction of Nutrition with Nuclear Receptors -- 5.2.2 Interaction of Nutrients with Metabolic Nuclear Receptors in Different Tissues During Obesity and Diabetes -- 5.3 Intestine |
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5.3.1 Physiological Role of FXR on Bile Acid (BA) Homeostasis and Hormone Secretion in the Intestine |
| Summary |
This book disseminates the cutting-edge knowledge pertaining to nutritional signaling activities in obesity and diabetes, including the regulatory mechanisms and perspectives of nutritional interventions for disease prevention. |
| Local Note |
eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America |
| Subject |
Metabolism.
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Metabolism -- Disorders.
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Nutrition.
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Cellular signal transduction.
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Cellular signal transduction |
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Metabolism |
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Metabolism -- Disorders |
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Nutrition |
| Genre/Form |
Electronic books.
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| Added Author |
Cheng, Zhiyong.
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| Other Form: |
Print version: Cheng, Zhiyong Nutritional Signaling Pathway Activities in Obesity and Diabetes Cambridge : Royal Society of Chemistry,c2020 9781788015578 |
| ISBN |
9781839160608 (electronic bk.) |
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1839160608 (electronic bk.) |
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9781839160615 (ebook) |
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1839160616 |
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9781788015578 |
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1788015576 |
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