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Title Medicinal Chemistry of Drugs Affecting the Nervous System.

Publication Info. Singapore : Bentham Science Publishers, 2020.

Item Status

Description 1 online resource (406 pages).
Physical Medium polychrome
Description text file
Series Medicinal Chemistry for Pharmacy Students Ser.
Medicinal Chemistry for Pharmacy Students Ser.
Note Description based upon print version of record.
Contents Cover -- Title -- Copyright -- End User License Agreement -- Contents -- Preface -- List of Contributors -- Drugs Affecting the Cholinergic System -- Cory R. Theberge1, Kim Lindsey-Goodrich2 and Ashok E. Philip3,* -- HISTORICAL PERSPECTIVES -- INTRODUCTORY CONCEPTS -- Choline and Acetylcholine -- Acetylcholine and Neurotransmission -- Cholinergic Neurochemistry: ACh Biosynthesis, Storage, Release, and Metabolism -- Cholinergic Receptors -- Muscarinic and Nicotinic Subtypes -- Clinical Use of Acetylcholine -- MUSCARINIC RECEPTOR AGONISTS -- MUSCARINIC RECEPTOR ANTAGONISTS (ANTICHOLINERGICS)
Donepezil (Aricept®) -- Pharmacokinetics -- Side effects/Drug Interactions -- Rivastigmine (Exelon®) 2000, Oral -- 2008, Patch -- Pharmacokinetics -- Side effects/Drug Interactions -- Galantamine (Razadyne®) 2001 -- Pharmacokinetics -- Side effects/Drug-interactions -- NMDA Receptor Antagonist: Memantine (Namenda®) 2003 -- Pharmacokinetics -- Side effects/Drug interactions -- Place in Therapy -- CASE STUDY -- What therapeutic modifications would you make at this time and why? -- Drug Discovery Case Study -- The Quaternary Advantage -- Ipratropium and the Kinetic Selectivity of Tiotropium
STUDENT SELF STUDY GUIDE -- PRACTICE QUESTIONS -- NOTES -- CONSENT FOR PUBLICATION -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENTS -- REFERENCES -- Drugs Affecting Adrenergic System -- M. O. Faruk1,* and Les Ramos2 -- HISTORICAL BACKGROUND -- THE INTRODUCTORY CONCEPTS -- Adrenergic Neurotransmitters -- Adrenergic Receptors (ARs) -- DRUGS AFFECTING ADRENERGIC SYSTEM: STRUCTURES, ACTIVITY, METABOLISM AND RELATED THERAPEUTIC CONSIDERATIONS -- The Antiadrenergics Affecting Synthesis, Storage, or Release of NE (Fig. 7) -- Metyrosine -- Reserpine -- Mechanism of Action -- Pharmacokinetics
Summary The primary objective of this 4-volume book series is to educate PharmD students on the subject of medicinal chemistry. The book set serves as a reference guide to pharmacists on aspects of the chemical basis of drug action. Medicinal Chemistry of Drugs Affecting the Nervous System is the second volume of the series and it presents 8 chapters focusing on a comprehensive account of drugs affecting the nervous system. The volume informs readers about the medicinal chemistry of relevant drugs, which includes the mechanism of drug action, detail structure activity relationships and metabolism as w.
Local Note eBooks on EBSCOhost EBSCO eBook Subscription Academic Collection - North America
Subject Neuropharmacology.
Neuropharmacology.
Autonomic nervous system -- Effect of drugs on.
Autonomic nervous system.
Central nervous system -- Effect of drugs on.
Central nervous system -- Effect of drugs on.
Central nervous system.
Pharmaceutical chemistry.
Pharmaceutical chemistry.
Genre/Form Electronic books.
Added Author Faruk, M. O.
Philip, Ashok E.
Other Form: Print version: Faruk, M. O. Medicinal Chemistry of Drugs Affecting the Nervous System Singapore : Bentham Science Publishers,c2020 9789811454059
ISBN 9811454078
9789811454073 (electronic book)